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Fig. 6 | Respiratory Research

Fig. 6

From: Mechanical ventilation enhances Acinetobacter baumannii-induced lung injury through JNK pathways

Fig. 6

Mechanical ventilation did not increase Acinetobacter baumannii (A.b.)-induced total cells and nitrite in the BALF, VCAM and MIP-2 expression in the lungs, and nitrite levels in the serum of JNK1−/− mice than those of WT mice. a Total cell counts in the BALF were increased in JNK1−/− mice receiving A.b. and ventilation. b Expression of pro-inflammatory chemokines and adhesion molecule mRNA in the lungs of WT and JNK1−/− mice receiving A.b. instillation and ventilation. VCAM expression was lower in the lungs of JNK1−/− mice than that of WT mice after A.b. instillation and ventilation. c, d The nitrite levels in the BALF and serum of WT and JNK1−/− mice receiving A.b. instillation and ventilation. Nitrite production in the BALF and serum was decreased in JNK1−/− mice. VCAM vascular cell adhesion molecule, BALF bronchoalveolar lavage fluid, NS normal saline. *P < 0.05, **P < 0.01, ***P < 0.001

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