From: Prediction of successful de-cannulation of tracheostomised patients in medical intensive care units
Characteristics | Successful de-cannulation (n = 149) | Failed de-cannulation (n = 197) | P value |
---|---|---|---|
Age, years | 57.9 (41.0–74.8) | 66.5 (52.6–80.4) | < 0.001 |
Male | 93 (62.4%) | 138 (70.1%) | 0.168 |
BMI, kg/m2 | 23.0 (19.0–27.0) | 21.6 (17.5–25.7) | 0.002 |
Underlying disease Malignant disease Respiratory disease Neurologic disease Genitourinary disease Cardiovascular disease | 48 (32.2%) 22 (14.8%) 18 (12.1%) 19 (12.8%) 22 (14.8%) | 87 (44.2%) 20 (10.2%) 54 (27.4%) 14 (7.1%) 30 (15.2%) | 0.032 0.256 0.001 0.113 > 0.999 |
Charlson co-morbidity index | 3.9 (1.1–6.7) | 5.0 (2.4–7.6) | < 0.001 |
Cause of MV support Pneumonia Extra-pulmonary sepsis Coma Pulmonary oedema ARDS Exacerbation of ILD Post CPR Central airway obstruction | 70 (47.0%) 24 (16.1%) 9 (6.0%) 10 (6.7%) 19 (12.8%) 4 (2.7%) 7 (4.7%) 6 (4.0%) | 68 (34.5%) 38 (19.3%) 46 (23.4%) 7 (3.6%) 8 (4.1%) 1 (0.5%) 18 (9.1%) 11 (5.6%) | 0.026 0.534 < 0.001 0.274 0.005 0.220 0.171 0.680 |
Duration of MV, days | 21.9 (2.2–39.6) | 18.1 (0.3–38.0) | 0.073 |
Charlson co-morbidity index | 3.9 (1.1–6.7) | 5.0 (2.4–7.6) | < 0.001 |
SOFA score | 2.7 (0.8–4.6) | 4.6 (2.0–7.2) | < 0.001 |
Positive CAM–ICU | 48 (32.2%) | 159 (80.7%) | < 0.001 |
Change of GCS Decreased No change Increased | 18 (12.1%) 56 (37.6%) 75 (50.3%) | 54 (27.4%) 71 (36.0%) 71 (36.0%) | 0.001 0.855 0.011 |
Suction frequency within 24 h | 8.0 (8.0–10.0) | 14.0 (12.0–16.0) | < 0.001 |
Weaning index Respiratory rate, /min PaO2/FiO2 ratio RSBI | 20.0 (16.0–23.0) 350.0 (286.0–411.0) 43.0 (32.0–55.0) | 19.0 (16.0–24.0) 311.0 (250.0–382.0) 49.0 (32.0–65.0) | 0.848 0.001 0.059 |
Laboratory findings Total bilirubin, mg/dL Creatinine, mg/dL Lactic acid, mmol/L | 0.9 (0.5–1.7) 0.9 (0.6–1.4) 1.1 (0.7–1.5) | 0.6 (0.4–1.1) 0.7 (0.5–1.1) 1.7 (0.7–2.7) | < 0.001 0.009 < 0.001 |
Vasopressor requirement | 5 (3.4%) | 28 (14.2%) | 0.001 |
CRRT | 4 (2.7%) | 7 (3.6%) | 0.883 |
Post-tracheostomy pneumonia during MV | 36 (24.2%) | 88 (44.7%) | < 0.001 |