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Fig. 2 | Respiratory Research

Fig. 2

From: Relationship between long non-coding RNA PCAT-1 expression and gefitinib resistance in non-small-cell lung cancer cells

Fig. 2

PCAT-1 knockdown led to gefitinib sensitivity in gefitinib resistant (GR) cells. a The efficiency of siRNA-mediated PCAT-1 knockdown was measured by qRT-PCR. b Cell viability was measured by CCK8 assay in H1299/GR cells transfected with si-NC or si- PCAT-1 after gefitinib treatment for 24 h. c Colony formation assays were performed to measure proliferation in GR cells transfected with si-NC or si- PCAT-1 after gefitinib treatment. d Transwell assays were performed to observe the migration of GR cells transfected with si-NC or si- PCAT-1 after gefitinib treatment. e Transwell assays were performed to observe the invasion of GR cells transfected with si-NC or si- PCAT-1 after gefitinib treatment. *, p < 0.05, **, p < 0.01

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