From: Defective monocyte-derived macrophage phagocytosis is associated with exacerbation frequency in COPD
Stable patients n = 92 | Repeatability analysis n = 36 | Paired exacerbation patients n = 39 | |
---|---|---|---|
Age (years) | 71.9 (8.7) | 69.3 (8.7) | 71.5 (8.0) |
FEV1 (L) | 1.34 (0.52) | 1.47 (0.58) | 1.27 (0.55) |
FEV1 (% predicted) | 54.6 (17.6) | 58.1 (18.4) | 52.7 (18.8) |
FVC (L) | 2.86 (0.87) | 2.90 (0.77) | 2.69 (0.93) |
FEV1/FVC (%) | 47.6 (13.4) | 50.7 (13.1) | 48.2 (15.4) |
Exacerbation frequency | 2.0 [1.0–3.0] | 2.0 [1.0–3.0] | 2.5 [1.5–3.5] |
Smoking pack years | 50.0 [28.4–71.5] | 45.3 [21.1–62.3] | 45.6 [24.5–76.5] |
ICS dose (beclomethasone equivalent μg) | 1000 [1000–2000] | 1500 [1000–2000] | 2000 [1000–2000] |
N (%) Male sex | 60 (65) | 24 (67) | 23 (59) |
N (%) Current smokers | 32 (35) | 17 (47) | 11 (28) |
N (%) Chronic bronchitis | 72 (78) | 31 (86) | 35 (90) |