From: Portable NIV for patients with moderate to severe COPD: two randomized crossover trials
Study II# | Period | With pNIV | Without pNIV | Treatment effect (95% CI) | P |
---|---|---|---|---|---|
pH | 1 | 7.37 ± 0.04 | 7.38 ± 0.02 | − 0.01 [− 0.02; − 0.001] | 0.033 |
2 | 7.38 ± 0.03 | 7.38 ± 0.04 | |||
PaCO2 [mmHg] | 1 | 53 ± 2.6 | 46.2 ± 5.3 | 1.1 [− 0.04; 2.3] | 0.06 |
2 | 47 ± 4.7 | 51.9 ± 3.3 | |||
PaO2 [mmHg] | 1 | 55.3 ± 7 | 61 ± 13.4 | − 3.6 [− 6.4; − 0.8] | 0.013 |
2 | 57.8 ± 9.7 | 59.2 ± 9.3 | |||
HCO3− [mmol/l] | 1 | 29.8 ± 3.2 | 26.6 ± 2.1 | − 0.3 [− 0.9; 0.3] | 0.29 |
2 | 26.9 ± 1.8 | 29.9 ± 2.6 | |||
SaO2 [%] | 1 | 88 ± 4.2 | 88.7 ± 4.7 | − 0.04 [− 1.4; 1.3] | 0.96 |
2 | 89.3 ± 4.2 | 88.8 ± 5.3 | |||
RRsys [mmHg] | 1 | 164.9 ± 37.2 | 164.8 ± 19.9 | 2.5 [− 8; 13] | 0.63 |
2 | 154.9 ± 13.5 | 160.5 ± 21.8 | |||
RRdia [mmHg] | 1 | 95.6 ± 16.5 | 92.3 ± 14 | 1.2 [− 5.8; 8.2] | 0.73 |
2 | 89.2 ± 10.1 | 90.7 ± 5.8 | |||
Heart rate [/min] | 1 | 86.1 ± 20 | 97.6 ± 21.3 | − 3.8 [− 8.6; 1.1] | 0.12 |
2 | 95.3 ± 20.4 | 91.4 ± 14.3 |