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Table 3 Study II#: blood gas analyses and vital parameters after exercise (N = 23)

From: Portable NIV for patients with moderate to severe COPD: two randomized crossover trials

Study II#

Period

With pNIV

Without pNIV

Treatment effect (95% CI)

P

pH

1

7.37 ± 0.04

7.38 ± 0.02

− 0.01 [− 0.02; − 0.001]

0.033

 

2

7.38 ± 0.03

7.38 ± 0.04

  

PaCO2 [mmHg]

1

53 ± 2.6

46.2 ± 5.3

1.1 [− 0.04; 2.3]

0.06

 

2

47 ± 4.7

51.9 ± 3.3

  

PaO2 [mmHg]

1

55.3 ± 7

61 ± 13.4

− 3.6 [− 6.4; − 0.8]

0.013

 

2

57.8 ± 9.7

59.2 ± 9.3

  

HCO3 [mmol/l]

1

29.8 ± 3.2

26.6 ± 2.1

− 0.3 [− 0.9; 0.3]

0.29

 

2

26.9 ± 1.8

29.9 ± 2.6

  

SaO2 [%]

1

88 ± 4.2

88.7 ± 4.7

− 0.04 [− 1.4; 1.3]

0.96

 

2

89.3 ± 4.2

88.8 ± 5.3

  

RRsys [mmHg]

1

164.9 ± 37.2

164.8 ± 19.9

2.5 [− 8; 13]

0.63

 

2

154.9 ± 13.5

160.5 ± 21.8

  

RRdia [mmHg]

1

95.6 ± 16.5

92.3 ± 14

1.2 [− 5.8; 8.2]

0.73

 

2

89.2 ± 10.1

90.7 ± 5.8

  

Heart rate [/min]

1

86.1 ± 20

97.6 ± 21.3

− 3.8 [− 8.6; 1.1]

0.12

 

2

95.3 ± 20.4

91.4 ± 14.3

  
  1. Bold values represent significant results
  2. PaO2 partial pressure of arterialized oxygen, PaCO2 partial pressure of arterialized carbon dioxide, HCO3 arterialized standard hydrogen carbonate, SaO2 Oxygen saturation, RRsys systolic blood pressure, RRdia diastolic blood pressure
  3. #Patients with long-term NIV