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Fig. 3 | Respiratory Research

Fig. 3

From: Single-cell characterization of a model of poly I:C-stimulated peripheral blood mononuclear cells in severe asthma

Fig. 3

Single-cell RNAseq of unstimulated cells. a UMAP of unstimulated PBMCs demonstrates a similar distribution of cells between severe asthma (SA) and healthy controls (HC). b Several pro-inflammatory transcripts including JAK1, IL7R, CCL4, NEAT1, CCL5, IL32, CFL1, and ACTG1 are highly expressed in cells from patients with SA (blue) compared to HC (orange). c Expression of the anti-inflammatory transcripts CMKLR1 and CD300LF were lower in SA than HC

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