Fig. 2

Single-cell RNAseq of PMBCs Identifies Distinct Clusters of Cells. a Top ten cluster markers for the five main cell types in all cells (n = 9390). b UMAP of all cell clusters including dendritic cells (n = 9414). c UMAP of all cell clusters by disease status, severe asthma (SA) (n = 6099) and healthy control (HC) (n = 3315). This figure demonstrates a similar distribution of cells across patients with severe asthma and healthy controls. d UMAP of all cell clusters by stimulation status, unstimulated (n = 4283) and poly I:C (n = 5131). This figure demonstrates a similar distribution of unstimulated and poly I:C stimulated cells