Fig. 4
Effects of AECs on the proliferation of PASMCs and AASMCs under hypoxia. a Co-culture with ATII significantly promoted the proliferation of PASMCs under hypoxia. *P < 0.05 vs. P (21% O2), ##P < 0.01 vs. P (5% O2). b Co-culture with ATII significantly promoted the proliferation of AASMCs under hypoxia. #P < 0.05 vs. A (5% O2). c ATII hypoxic culture medium significantly promoted the proliferation of PASMCs. *P < 0.05 vs. P (21% O2), #P < 0.05 vs. P (5% O2) d ATII hypoxic culture medium significantly promoted the proliferation of AASMCs. **P < 0.01 vs. A (21% O2), ##P < 0.01 vs. A (5% O2). The growth of PASMCs or AASMCs under 21% O2 was set as 100% and the proliferation of treated cells was calculated as a percentage of them. P:  PASMCs, A:  AASMCs, ANCM ATII normoxic culture medium, AHCM ATII hypoxic culture medium, n = 8, Data are means ± S.D