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Table 2 Exacerbation status up to Week 16 by fibrinogen quartile and withdrawal status

From: InforMing the PAthway of COPD Treatment (IMPACT) trial: fibrinogen levels predict risk of moderate or severe exacerbations

 

Week 16 fibrinogen data

No Week 16 fibrinogen data

 

Exacerbation

Quartile 1

N = 2017

Quartile 2

N = 2025

Quartile 3

N = 2002

Quartile 4

N = 2050

Withdrewa

N = 1195

Otherb

N = 1066

Total

N = 10,355

Yes, n (%)

452 (22)

476 (24)

509 (25)

609 (30)

547 (46)

271 (25)

2864 (28)

No, n (%)

1565 (78)

1549 (76)

1493 (75)

1441 (70)

648 (54)

795 (75)

7491 (72)

  1. Quartile 1, fibrinogen value < 25th percentile; Quartile 2, fibrinogen value > 25th percentile and < median; Quartile 3, fibrinogen value ≥ median and < 75th percentile; Quartile 4, fibrinogen value ≥ 75th percentile
  2. aPatients who discontinued study treatment/withdrew from the study on or prior to Week 16 and did not have a fibrinogen result at Week 16;
  3. bPatients who did not discontinue study treatment/withdraw from the study on or prior to Week 16 but had a missing fibrinogen result at Week 16