Skip to main content

Table 3 Levels of proADM, proANP and copeptin in patients with mild, moderate and severe OSA, as assessed by the AHI, at baseline

From: Copeptin, pro-atrial natriuretic peptide and pro-adrenomedullin as markers of hypoxic stress in patients with obstructive sleep apnea—a prospective intervention study

Baseline Levels

OSA severity

p-value (Kruskal -Wallis Test)

Mild OSA (N = 86)

5 ≤ AHI < 15

Moderate OSA (N = 78)

15 ≤ AHI < 30

Severe OSA (N = 68)

AHI ≥ 30

proADM (nmol/l)

0.60 (0.50–0.74)

0.62 (0.55–0.75)

0.63 (0.59–0.79)

p = 0.222

proANP (pmol/l)

55.34 (42.61–79.64)

54.81 (40.3–85.05)

61.04 (44.77–98.37)

p = 0.672

Copeptin (pmol/l)

7.15 (4.57–10.37)

7.37 (5.3–9.64)

7.92 (5.08–12.81)

p = 0.375