From: Copeptin, pro-atrial natriuretic peptide and pro-adrenomedullin as markers of hypoxic stress in patients with obstructive sleep apnea—a prospective intervention study
6 months CPAP (N = 100)
No OSA (N = 26)
p-value (Kruskal–Wallis test)
proADM (nmol/l)
0.60 (0.50–0.70)
0.56 (0.50–0.70)
0.420
proANP (pmol/l)
58.38 (40.73–98.74)
47.36 (31.92–69.88)
0.118
Copeptin (pmol/l)
7.95 (4.56–11.48)
4.80 (2.93–7.13)
0.001