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Fig. 3 | Respiratory Research

Fig. 3

From: Adhatoda Vasica attenuates inflammatory and hypoxic responses in preclinical mouse models: potential for repurposing in COVID-19-like conditions

Fig. 3

Enriched gene expression pattern of AV treatment may prevent the SARS-CoV2 infection-induced transcriptional changes a The volcano plot represents the variable expression status of genes upon AV-D2 and AV-D4 treatment in mice's lungs compared to the vehicle group. Red and green coloured dots represent up and down-regulated genes (FC > |2|, P-value < 0.05). b Heatmap represents the top 50 most variable genes in the AV-D4 group and their expression status in Vehicle, AV-D2, and AV-D4 group. c Enriched pathways and biological process in up-regulated and down-regulated genes after AV treatment compared to vehicle mice group

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Respiratory Research

ISSN: 1465-993X

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