Longitudinal analysis of sinus microbiota post endoscopic surgery in patients with cystic fibrosis and chronic rhinosinusitis: a pilot study

Table 1 Demographic and clinical data collected from the four patients in this study

Patient	Collection timepoint^a	Sample collection procedure	Age^b	Sex	Smoker	Ethnicity	CF diagnostic criteria	Age at CF diagnosis	Age at CRS diagnosis	Lung transplant	Nasal polyposis	Lund-Mackay
P01	Baseline	FHFESS	21	M	No	NZE	Δf508	< 5	11	No	Yes	21
	6	Clinic
	13	Clinic
	15	Clinic
	18	FHFESS—revision
P02	Baseline	FHFESS	36	F	No	NZE	Δf508	< 5	Unknown	No	Yes	12
	2	Clinic
	6	Clinic
	11	Clinic
P03	Baseline	FHFESS	50	F	Ex	Maori	Positive sweat tests, no CFTR mutation on genotyping^c	> 18	42	No	Yes	13
	3	Clinic
	6	Clinic
	12	Clinic
P04	Baseline	FHFESS—revision	31	F	No	NZE	Δf508	< 5	21	2012	Yes	19
	3	Clinic
	6	Clinic
	7	FHFESS—revision
	11	Clinic

CF cystic fibrosis, CRS chronic rhinosinusitis, FHFESS full house functional endoscopic sinus surgery, NZE New Zealand European
^aCollection timepoint refers to months from baseline sample collection
^bAge at baseline sample collection
^cFulfils diagnostic criteria on the grounds of appropriate phenotypic features (chronic sinopulmonary disease) and laboratory evidence of CFTR dysfunction (sweat chloride > 60 mmol/L on two separate occasions)

ISSN: 1465-993X