TY - JOUR AU - Biondini, Davide AU - Cocconcelli, Elisabetta AU - Bernardinello, Nicol AU - Lorenzoni, Giulia AU - Rigobello, Chiara AU - Lococo, Sara AU - Castelli, Gioele AU - Baraldo, Simonetta AU - Cosio, Manuel G. AU - Gregori, Dario AU - Saetta, Marina AU - Balestro, Elisabetta AU - Spagnolo, Paolo PY - 2021 DA - 2021/04/01 TI - Prognostic role of MUC5B rs35705950 genotype in patients with idiopathic pulmonary fibrosis (IPF) on antifibrotic treatment JO - Respiratory Research SP - 98 VL - 22 IS - 1 AB - A common variant located in the promoter region of MUC5B (rs35705950) is the strongest risk factor for sporadic and familiar IPF, as well as a predictor of outcome. However, there are no data on the effect of MUC5B rs35705950 genotype on the prognosis of IPF patients on antifibrotic treatment. The aim of this study is to determine, in a phenotypically well-characterized population of patients with IPF treated with antifibrotics, the impact of MUC5B rs35705950 genotype on disease progression and survival. SN - 1465-993X UR - https://doi.org/10.1186/s12931-021-01694-z DO - 10.1186/s12931-021-01694-z ID - Biondini2021 ER -