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Fig. 5 | Respiratory Research

Fig. 5

From: Artesunate ameliorates cigarette smoke-induced airway remodelling via PPAR-γ/TGF-β1/Smad2/3 signalling pathway

Fig. 5

Effects of artesunate on expression of PPAR-γand activation of TGF-β1/Smad2/3 signalling in HBSM cells (n = 3) and rat lungs (n = 6). The expressions of PPAR-γ, p-Smad2/3, Smad2/3 and GAPDH in rat lungs (a, b) and HBSM cells (d, e) were determined using Western blot. The levels of TGF-β1 in supernatant of BALF of rats (c) and HBSM cells (f) were determined using ELISA test. Data were expressed as mean ± SEM. ##P < 0.01 compared to control group using unpaired t-test; *P < 0.05 and, **P < 0.01 and ns means no significant difference compared to CS group using one-way ANOVA with Dunnett test for selected pairs. Arts Artesunate

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Respiratory Research

ISSN: 1465-993X

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