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Table 3 Results from the random coefficient models for change in PD15adj., (coefficients per standard deviation of Log10 sRAGE)

From: Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COPD

Cohort Effect on baseline PD15adj (g/L per SD Log10 sRAGE) Effect on annual change in PD15adj (g/L/year per SD Log10 sRAGE
Coefficient (SE) p-value Coefficient (SE) p-value
COPDGene QBR (n = 1402) 3.99 (0.0.54) < 0.0001 − 0.10 (0.08) 0.18
ECLIPSE (n = 1699) 5.12 (0.47) < 0.0001 0.19 (0.07) 0.009
SCCOR (n = 399) 2.40 (0.77) 0.0343 0.02 (0.08) 0.81
SPIROMICS (n = 1406) 4.61 (0.56) < 0.0001 − 0.02 (0.06) 0.75