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Table 3 Results from the random coefficient models for change in PD15adj., (coefficients per standard deviation of Log10 sRAGE)

From: Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COPD

Cohort

Effect on baseline PD15adj (g/L per SD Log10 sRAGE)

Effect on annual change in PD15adj (g/L/year per SD Log10 sRAGE

Coefficient (SE)

p-value

Coefficient (SE)

p-value

COPDGene QBR (n = 1402)

3.99 (0.0.54)

< 0.0001

− 0.10 (0.08)

0.18

ECLIPSE (n = 1699)

5.12 (0.47)

< 0.0001

0.19 (0.07)

0.009

SCCOR (n = 399)

2.40 (0.77)

0.0343

0.02 (0.08)

0.81

SPIROMICS (n = 1406)

4.61 (0.56)

< 0.0001

− 0.02 (0.06)

0.75