Table 2 Results from the random coefficient models for change in FEV1, (coefficients per standard deviation of Log10 sRAGE)
From: Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COPD
Cohort | Effect on baseline FEV1 (ml per SD Log10 sRAGE) | Effect on annual change in FEV1 (ml/year per SD Log10 sRAGE) | ||
|---|---|---|---|---|
Coefficient (SE) | p-value | Coefficient (SE) | p-value | |
COPDGene QBR (n = 1408) | 127.90 (21.35) | < 0.0001 | 0.96 (1.48) | 0.52 |
ECLIPSE (n = 1847) | 66.65 (10.80) | < 0.0001 | 4.15 (1.88) | 0.0272 |
SCCOR (n = 399) | 74.21 (29.45) | 0.0121 | 4.06 (2.41) | 0.09 |
SPIROMICS (n = 1408) | 156.36 (22.27) | < 0.0001 | − 0.89 (1.81) | 0.62 |