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Table 2 Results from the random coefficient models for change in FEV1, (coefficients per standard deviation of Log10 sRAGE)

From: Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COPD

Cohort Effect on baseline FEV1 (ml per SD Log10 sRAGE) Effect on annual change in FEV1 (ml/year per SD Log10 sRAGE)
Coefficient (SE) p-value Coefficient (SE) p-value
COPDGene QBR (n = 1408) 127.90 (21.35) < 0.0001 0.96 (1.48) 0.52
ECLIPSE (n = 1847) 66.65 (10.80) < 0.0001 4.15 (1.88) 0.0272
SCCOR (n = 399) 74.21 (29.45) 0.0121 4.06 (2.41) 0.09
SPIROMICS (n = 1408) 156.36 (22.27) < 0.0001 − 0.89 (1.81) 0.62