Fig. 3
From: Enhanced lung inflammatory response in whole-body compared to nose-only cigarette smoke-exposed mice
Histological evaluation of lung inflammation. a H&E staining of lung slides (× 200) of a representative nose-only and whole-body mouse lung slide. Semi-quantitative scoring of b pigmented alveolar macrophages (thin arrows), c lymphoid aggregates (thick arrows) and d diffuse lymphoid inflammation. e Relative mRNA expression of interferon (IFN)-γ, interleukin (IL)-12p40, IL-17, IL-23, IL-4, IL-13, IL-10 and transforming growth factor (TGF)-β. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. Data are expressed as median and IQR (n = 8–15)