Table 5 Identified clusters, number of differentially expressed genes in case vs. control, mean % of cells belonging to this cluster both in cases and controls, fold change differences between cluster percentage and the p value of the comparison of the cluster frequency in cases vs. controls both with t-test and Wilcoxon-test

27.97 ± 10.74

5.15 ± 1.57

5.43

0.02

0.057

23.80 ± 12.90

11.24 ± 4.84

2.12

0.18

0.23

11.18 ± 6.48

21.86 ± 9.80

− 1.96

0.14

0.11

3.85 ± 2.89

22.14 ± 27.41

− 5.75

0.23

0.4

9.17 ± 3.90

2.37 ± 0.52

3.87

0.03

0.057

2.11 ± 1.00

11.68 ± 9.02

− 5.54

0.08

0.23

0.99 ± 0.59

6.80 ± 7.95

− 6.84

0.19

0.23

1.84 ± 0.98

6.18 ± 4.36

− 3.35

0.10

0.23

4.12 ± 2.52

0.96 ± 0.32

− 4.28

0.09

0.057

1.75 ± 0.68

3.71 ± 2.07

− 2.12

0.13

0.11

2.02 ± 0.95

2.83 ± 1.50

− 1.40

0.41

0.63

3.17 ± 1.62

0.27 ± 0.07

11.60

0.03

0.057

1.35 ± 0.81

2.72 ± 2.16

− 2.02

0.29

0.63

2.60 ± 1.91

0.46 ± 0.36

5.71

0.12

0.11

1.93 ± 1.10

0.33 ± 0.29

5.85

0.06

0.23

1.32 ± 0.79

0.91 ± 0.24

1.44

0.44

0.63

0.84 ± 0.35

0.39 ± 0.25

2.17

0.12

0.11