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Table 3 Clinical and demographics of the Lung Genomics Research Consortium (LGRC) Cohort (used for QKI and IGFBP5 gene expression analysis)

From: Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD

 

Control

COPD

Number of subjects

108

219

Age, year, mean (SD)

63.6 (11.4)

64.7 (9.7)

Gender (% Female)

55%

43%

Smoking status, (%)

  

 Never

30%

5.50%

 Current

1.90%

6.40%

 Ever

58%

86.70%

 Unknown

10.10%

1.40%

Pulmonary function, mean (SD)

 FEV1, % predicted

95 (12.6)

50.6 (24.0)

 FVC, % predicted

94.4 (13.1)

73,8 (19.5)

 DLCO, % predicted

84.1 (16.7)

56.6 (23.1)

 Emphysema, % mean (SD)

 

15.4 (17.1)

  1. DLCO diffusing capacity of the lung for carbon monoxide