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Table 5 Association between exposure to air pollutants and the incidence of AE-IIPs

From: Exposure to PM2.5 is a risk factor for acute exacerbation of surgically diagnosed idiopathic pulmonary fibrosis: a case–control study

Air pollutant

Increase

Adjusted OR

95% CI

p-value

SO2

10 ppb

1.30

0.19–8.69

0.79

NO

10 ppb

1.50

1.19–1.88

0.001

NO2

10 ppb

1.99

1.22–3.27

0.006

NOX

10 ppb

1.29

1.08–1.53

0.004

CO

10 ppb

1.01

0.99–1.03

0.16

O3

10 ppb

0.90

0.64–1.27

0.55

PM2.5

10 µg/m3

2.88

1.69–4.91

 < 0.001

PM10

10 µg/m3

1.11

0.70–1.78

0.65

  1. Results are presented as adjusted ORs and 95% CIs; the model was adjusted for temperature, humidity, age, sex, smoking status (pack-years), percentage of predicted value of FVC and DLCO and neighbourhood-level factors. The adjusted ORs are presented per 10-unit increase in levels of SO2 (ppb), NO (ppb), NO2 (ppb), NOX (ppb), CO (ppb), O3 (ppb), PM2.5 (µg/m3), and PM10 (µg/m3). p-values statistically significant are presented in bold
  2. AE-IPF acute exacerbation of idiopathic pulmonary fibrosis, OR odds ratio, CI confidence interval, FVC forced vital capacity, DLCO diffusing capacity of the lung for carbon monoxide, SO2 sulfur dioxide, NO nitric oxide, NO2 nitrogen dioxide, NOX nitrogen oxides, CO carbon monoxide, O3 ozone, PM2.5 particulate matter < 2.5 µm, PM10 particulate matter < 10 µm