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Table 5 Association between exposure to air pollutants and the incidence of AE-IIPs

From: Exposure to PM2.5 is a risk factor for acute exacerbation of surgically diagnosed idiopathic pulmonary fibrosis: a case–control study

Air pollutant Increase Adjusted OR 95% CI p-value
SO2 10 ppb 1.30 0.19–8.69 0.79
NO 10 ppb 1.50 1.19–1.88 0.001
NO2 10 ppb 1.99 1.22–3.27 0.006
NOX 10 ppb 1.29 1.08–1.53 0.004
CO 10 ppb 1.01 0.99–1.03 0.16
O3 10 ppb 0.90 0.64–1.27 0.55
PM2.5 10 µg/m3 2.88 1.69–4.91  < 0.001
PM10 10 µg/m3 1.11 0.70–1.78 0.65
  1. Results are presented as adjusted ORs and 95% CIs; the model was adjusted for temperature, humidity, age, sex, smoking status (pack-years), percentage of predicted value of FVC and DLCO and neighbourhood-level factors. The adjusted ORs are presented per 10-unit increase in levels of SO2 (ppb), NO (ppb), NO2 (ppb), NOX (ppb), CO (ppb), O3 (ppb), PM2.5 (µg/m3), and PM10 (µg/m3). p-values statistically significant are presented in bold
  2. AE-IPF acute exacerbation of idiopathic pulmonary fibrosis, OR odds ratio, CI confidence interval, FVC forced vital capacity, DLCO diffusing capacity of the lung for carbon monoxide, SO2 sulfur dioxide, NO nitric oxide, NO2 nitrogen dioxide, NOX nitrogen oxides, CO carbon monoxide, O3 ozone, PM2.5 particulate matter < 2.5 µm, PM10 particulate matter < 10 µm