| UIP | Probable UIP | Indeterminate for UIP | Alternative diagnosis |
---|
PPV | 0.87 (0.60, 0.98) | 0.38 (0.14, 0.68) | 0.27 (0.06, 0.61) | 0.21 (0.11, 0.33) |
NPV | 0.76 (0.65, 0.84) | 0.67 (0.56, 0.77) | 0.66 (0.55, 0.76) | 0.45 (0.29, 0.62) |
Sensitivity | 0.38 (0.22, 0.56) | 0.15 (0.05, 0.31) | 0.09 (0.02, 0.24) | 0.38 (0.22, 0.56) |
Specificity | 0.97 (0.90, 1.00) | 0.88 (0.78, 0.95) | 0.90 (0.80, 0.96) | 0.25 (0.16, 0.37) |
- Test characteristics, including positive predictive value (PPV; e.g., Pr(histologic UIP|CT UIP)), negative predictive value (NPV; e.g., Pr(not histologic UIP|not CT UIP)), sensitivity (e.g., Pr(CT UIP|histologic UIP)), and specificity (e.g., Pr(not CT UIP| not histologic UIP)) were determined for all CT categories against histopathologic UIP. To quantify the uncertainty of these estimates, 95% confidence intervals were computed