Fig. 5
From: Lack of CD34 delays bacterial endotoxin-induced lung inflammation
a–e: a Lung H&E Histology (0, 3 h) and b (0, 9, 15, 24 h: Representative images from H&E stained perfused left lung from 0-h (no LPS; WT, N = 7; CD34 KO, N = 7), and 3 h (WT, N = 6; CD34 KO, N = 6) post-LPS treatment. Note at 24 h, there are leukocytes adhering to the large blood vessel (BV) despite perfusion of lungs; alveolar infiltration near a bronchus (B) is significant in both strains showing dissemination of inflammation. Scale bar: a: 200 μm, inset 50 μm; b: 25 μm; c–e Histological Scoring of Inflammation in lung sections: c Perivascular, d peribronchiolar and e septal inflammation scores from H&E stained left lung. For perivascular, peribronchial and septal inflammation scores, interaction effect was non-significant but main effect of time-point (*) and genotype (°) were significant. No difference in perivascular, peribronchiolar, and septal inflammation score in WT vs CD34 KO at any of the time-points