TY - JOUR AU - Tilley, A. E. AU - Walters, M. S. AU - Shaykhiev, R. PY - 2015 DA - 2015// TI - Cilia Dysfunction in Lung Disease JO - Annu Rev Physiol VL - 77 UR - https://doi.org/10.1146/annurev-physiol-021014-071931 DO - 10.1146/annurev-physiol-021014-071931 ID - Tilley2015 ER - TY - JOUR AU - Yang, J. AU - Zuo, W. -. L. AU - Fukui, T. PY - 2017 DA - 2017// TI - Smoking-dependent distal-to-proximal repatterning of the adult human small airway epithelium JO - Am J Respir Crit Care Med VL - 196 UR - https://doi.org/10.1164/rccm.201608-1672OC DO - 10.1164/rccm.201608-1672OC ID - Yang2017 ER - TY - JOUR AU - Gohy, S. AU - Carlier, F. M. AU - Fregimilicka, C. PY - 2019 DA - 2019// TI - Altered generation of ciliated cells in chronic obstructive pulmonary disease JO - Sci Rep VL - 9 UR - https://doi.org/10.1038/s41598-019-54292-x DO - 10.1038/s41598-019-54292-x ID - Gohy2019 ER - TY - STD TI - Perotin J-M, Coraux C, Lagonotte E, et al. Alteration of primary cilia in COPD. Eur Respir J 2018;52. doi:https://doi.org/10.1183/13993003.00122-2018 ID - ref4 ER - TY - JOUR AU - Lam, H. C. AU - Cloonan, S. M. AU - Bhashyam, A. R. PY - 2013 DA - 2013// TI - Histone deacetylase 6–mediated selective autophagy regulates COPD-associated cilia dysfunction JO - Journal of Clinical Investigation VL - 123 UR - https://doi.org/10.1172/JCI69636 DO - 10.1172/JCI69636 ID - Lam2013 ER - TY - JOUR AU - Hessel, J. AU - Heldrich, J. AU - Fuller, J. PY - 2014 DA - 2014// TI - Intraflagellar transport gene expression associated with short cilia in smoking and COPD JO - PLoS ONE VL - 9 UR - https://doi.org/10.1371/journal.pone.0085453 DO - 10.1371/journal.pone.0085453 ID - Hessel2014 ER - TY - JOUR AU - Wain, L. V. AU - Sayers, I. AU - Soler Artigas, M. PY - 2014 DA - 2014// TI - Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction JO - PLoS Genet VL - 10 UR - https://doi.org/10.1371/journal.pgen.1004314 DO - 10.1371/journal.pgen.1004314 ID - Wain2014 ER - TY - JOUR AU - Qiao, D. AU - Ameli, A. AU - Prokopenko, D. PY - 2018 DA - 2018// TI - Whole exome sequencing analysis in severe chronic obstructive pulmonary disease JO - Hum Mol Genet VL - 27 UR - https://doi.org/10.1093/hmg/ddy269 DO - 10.1093/hmg/ddy269 ID - Qiao2018 ER - TY - JOUR PY - 2019 DA - 2019// TI - UniProt: a worldwide hub of protein knowledge JO - Nucleic Acids Res VL - 47 UR - https://doi.org/10.1093/nar/gky1049 DO - 10.1093/nar/gky1049 ID - ref9 ER - TY - STD TI - Wheway G, Genomics England Research Consortium, Mitchison HM. Opportunities and Challenges for Molecular Understanding of Ciliopathies–The 100,000 Genomes Project. Front Genet 2019;10:127. doi:https://doi.org/10.3389/fgene.2019.00127 ID - ref10 ER - TY - JOUR AU - Nogales-Cadenas, R. AU - Abascal, F. AU - Diez-Perez, J. PY - 2009 DA - 2009// TI - CentrosomeDB: a human centrosomal proteins database JO - Nucleic Acids Res VL - 37 UR - https://doi.org/10.1093/nar/gkn815 DO - 10.1093/nar/gkn815 ID - Nogales-Cadenas2009 ER - TY - JOUR AU - Arnaiz, O. AU - Malinowska, A. AU - Klotz, C. PY - 2009 DA - 2009// TI - Cildb: a knowledgebase for centrosomes and cilia JO - Database UR - https://doi.org/10.1093/database/bap022 DO - 10.1093/database/bap022 ID - Arnaiz2009 ER - TY - STD TI - SYSCILIA Study Group, van Dam TJ, Wheway G, et al. The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium. Cilia 2013;2:7. doi:https://doi.org/10.1186/2046-2530-2-7 ID - ref13 ER - TY - JOUR AU - Dam, T. J. P. AU - Kennedy, J. AU - Lee, R. PY - 2019 DA - 2019// TI - CiliaCarta: An integrated and validated compendium of ciliary genes JO - PLoS ONE VL - 14 UR - https://doi.org/10.1371/journal.pone.0216705 DO - 10.1371/journal.pone.0216705 ID - Dam2019 ER - TY - JOUR AU - Patir, A. AU - Fraser, A. M. AU - Barnett, M. W. PY - 2020 DA - 2020// TI - The transcriptional signature associated with human motile cilia JO - Sci Rep VL - 10 UR - https://doi.org/10.1038/s41598-020-66453-4 DO - 10.1038/s41598-020-66453-4 ID - Patir2020 ER - TY - JOUR AU - Schiller, H. B. AU - Montoro, D. T. AU - Simon, L. M. PY - 2019 DA - 2019// TI - The human lung cell atlas: a high-resolution reference map of the human lung in health and disease JO - Am J Respir Cell Mol Biol VL - 61 UR - https://doi.org/10.1165/rcmb.2018-0416TR DO - 10.1165/rcmb.2018-0416TR ID - Schiller2019 ER - TY - JOUR AU - Belgacemi, R. AU - Luczka, E. AU - Ancel, J. PY - 2020 DA - 2020// TI - Airway epithelial cell differentiation relies on deficient Hedgehog signalling in COPD JO - EBioMedicine VL - 51 UR - https://doi.org/10.1016/j.ebiom.2019.11.033 DO - 10.1016/j.ebiom.2019.11.033 ID - Belgacemi2020 ER - TY - JOUR AU - Ancel, J. AU - Belgacemi, R. AU - Perotin, J. -. M. PY - 2020 DA - 2020// TI - Sonic hedgehog signalling as a potential endobronchial biomarker in COPD JO - Respir Res VL - 21 UR - https://doi.org/10.1186/s12931-020-01478-x DO - 10.1186/s12931-020-01478-x ID - Ancel2020 ER - TY - JOUR AU - Paci, P. AU - Fiscon, G. AU - Conte, F. PY - 2020 DA - 2020// TI - Integrated transcriptomic correlation network analysis identifies COPD molecular determinants JO - Sci Rep VL - 10 UR - https://doi.org/10.1038/s41598-020-60228-7 DO - 10.1038/s41598-020-60228-7 ID - Paci2020 ER - TY - JOUR AU - Wang, L. AU - Fang, R. AU - Zhu, M. PY - 2021 DA - 2021// TI - Integrated gene-based and pathway analyses using UK Biobank data identify novel genes for chronic respiratory diseases JO - Gene VL - 767 UR - https://doi.org/10.1016/j.gene.2020.145287 DO - 10.1016/j.gene.2020.145287 ID - Wang2021 ER - TY - JOUR AU - Wang, X. AU - Rojas-Quintero, J. AU - Zhang, D. PY - 2020 DA - 2020// TI - A disintegrin and metalloproteinase domain-15 deficiency leads to exaggerated cigarette smoke-induced chronic obstructive pulmonary disease (COPD)-like disease in mice JO - Mucosal Immunol UR - https://doi.org/10.1038/s41385-020-0325-3 DO - 10.1038/s41385-020-0325-3 ID - Wang2020 ER - TY - JOUR AU - Wilk, J. B. AU - Shrine, N. R. G. AU - Loehr, L. R. PY - 2012 DA - 2012// TI - Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction JO - Am J Respir Crit Care Med VL - 186 UR - https://doi.org/10.1164/rccm.201202-0366OC DO - 10.1164/rccm.201202-0366OC ID - Wilk2012 ER - TY - JOUR AU - Yao, T. -. C. AU - Du, G. AU - Han, L. PY - 2014 DA - 2014// TI - Genome-wide association study of lung function phenotypes in a founder population JO - J Allergy Clin Immunol VL - 133 UR - https://doi.org/10.1016/j.jaci.2013.06.018 DO - 10.1016/j.jaci.2013.06.018 ID - Yao2014 ER - TY - JOUR AU - Wang, X. AU - Zhang, D. AU - Higham, A. PY - 2020 DA - 2020// TI - ADAM15 expression is increased in lung CD8+ T cells, macrophages, and bronchial epithelial cells in patients with COPD and is inversely related to airflow obstruction JO - Respir Res VL - 21 UR - https://doi.org/10.1186/s12931-020-01446-5 DO - 10.1186/s12931-020-01446-5 ID - Wang2020 ER - TY - JOUR AU - Shrine, N. AU - Guyatt, A. L. AU - Erzurumluoglu, A. M. PY - 2019 DA - 2019// TI - New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries JO - Nat Genet VL - 51 UR - https://doi.org/10.1038/s41588-018-0321-7 DO - 10.1038/s41588-018-0321-7 ID - Shrine2019 ER -