Skip to main content
Fig. 5 | Respiratory Research

Fig. 5

From: PGC-1α regulates airway epithelial barrier dysfunction induced by house dust mite

Fig. 5

Effects of PAR2 and TLR4 inhibitors on HDM-mediated downregulation of mitochondrial biogenesis and junctional proteins. af BEAS-2B cells were treated with various concentrations of GB83, a PAR2 inhibitor or LPS-RS, a TLR4 inhibitor for 30 min. Subsequently, the cells were stimulated with HDM (100 μg/ml) for 24 h and the cells were harvested. The expressions of PGC-1α, E-cadherin, and ZO-1 in cells were analyzed by western blotting. (LPS-RS, n = 3; others, n = 4). Data are expressed as means ± SD. *p < 0.05, **p < 0.01

Back to article page
\