The association between hospital length of stay before rapid response system activation and clinical outcomes: a retrospective multicenter cohort study

Table 3 Effects of the hospital LOS before RRS activation on the clinical outcomes

Variables	Early deterioration (N = 5779)	Late deterioration (N = 5833)	P value
Primary outcome
28-day mortality	1051 (18.2%)	1483 (25.4%)
Unadjusted OR	1.00	1.53 (1.40–1.68)	< 0.001
Adjusted OR¹	1.00	1.60 (1.44–1.77)	< 0.001
Secondary outcome
In-hospital mortality	1209 (20.9%)	1758 (30.2%)
Unadjusted OR	1.00	1.63 (1.50–1.78)	< 0.001
Adjusted OR^a	1.00	1.71 (1.55–1.88)	< 0.001
ICU admission	1611 (27.9%)	1774 (30.4%)
Unadjusted OR	1.00	1.13 (1.04–1.23)	0.003
Adjusted OR^a	1.00	1.10 (1.01–1.20)	0.030
Hospital LOS after RRS activation (days)	10 (5–20)	14 (6–27)
Unadjusted IRR	1.00	1.33 (1.28–1.38)	< 0.001
Adjusted IRR^a	1.00	1.30 (1.25–1.35)	< 0.001
LOS in ICU^b (days)	4 (2–9)	5 (3–10)
Unadjusted IRR	1.00	1.21 (1.13–1.30)	< 0.001
Adjusted IRR^a	1.00	1.22 (1.14–1.31)	< 0.001

LOS length of stay, RRS rapid response system, OR odds ratio, IRR incidence rate ratio, ICU intensive care unit
^aMultivariable logistic regression and negative binomial regression were performed with adjusting for following confounding variables: age, department of admission (medical vs. surgical), whether patients were in postoperative state, comorbidities of solid cancer, hematological malignancy, chronic lung disease, hepatobiliary disease, or cerebrovascular disease, whether DNR (do-not-resuscitate) discussion was made after RRS activation, and NEWS2 (national early warning score 2)
^bAnalysis on LOS in ICU included only patients who were admitted to the ICU

ISSN: 1465-993X