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Table 2 Severity of illness at RRS activation and interventions by RRS team

From: The association between hospital length of stay before rapid response system activation and clinical outcomes: a retrospective multicenter cohort study

Variables

Total

Early

Late

P value

patients

deterioration

deterioration

(N = 11,612)

(N = 5779)

(N = 5833)

Mean blood pressure (mmHg)

83 (66–98)

82 (66–97)

83 (66–98)

0.289

Heart rate (rate/min)

102 (84–120)

100 (82–120)

104 (86–122)

 < 0.001

Respiratory rate (rate/min)

22 (18–28)

22 (18–28)

22 (18–28)

0.46

Body temperature (°C)

36.9 (36.5–37.6)

36.9 (36.5–37.6)

36.9 (36.5–37.6)

0.36

Alert mental status

7968 (68.6%)

4204 (72.8%)

3764 (64.5%)

 < 0.001

Need for supplementary oxygen therapy

6880 (59.3%)

3339 (57.8%)

3541 (60.7%)

0.001

MEWS

4 (2–5)

4 (2–5)

4 (2–6)

 < 0.001

NEWS2

7 (5–10)

7 (5–10)

8 (5–10)

 < 0.001

SOFA scorea

5 (3–7)

4 (2–7)

5 (3–8)

 < 0.001

Intervention of RRS team

    

Tracheal intubation

1525 (13.1%)

720 (12.5%)

805 (13.8%)

0.032

Mechanical ventilation

1400 (12.1%)

655 (11.3%)

745 (12.8%)

0.017

High flow nasal cannula

900 (7.8%)

458 (7.9%)

442 (7.6%)

0.484

Noninvasive ventilation

172 (1.5%)

103 (1.8%)

69 (1.2%)

0.008

Renal replacement therapy

499 (4.3%)

241 (4.2%)

258 (4.4%)

0.501

ACLS including CPR

453 (3.9%)

201 (3.5%)

252 (4.3%)

0.019

ECLS

49 (0.4%)

26 (0.5%)

23 (0.4%)

0.644

Central venous catheter

831 (7.2%)

415 (7.2%)

416 (7.1%)

0.918

Antimicrobial therapy

745 (6.4%)

325 (5.6%)

420 (7.2%)

0.001

Vasopressor/inotrope

1443 (12.4%)

705 (12.2%)

738 (12.7%)

0.46

Transfusion

659 (5.7%)

307 (5.3%)

352 (6.0%)

0.093

Discussion regarding

1226 (10.6%)

541 (9.4%)

685 (11.7%)

 < 0.001

do-not-resuscitate order

  1. RRS rapid response system, MEWS modified early weaning score, NEWS2 national early warning score 2, SOFA sequential organ failure assessment, ACLS advanced cardiac life support, CPR cardiopulmonary resuscitation, ECLS extracorporeal life support
  2. aSOFA scores were available in 6,733 (58.0%) patients who had relevant laboratory test results including arterial blood gas analysis