Total | Calverley | CCLS | ECLIPSE | EUROSCOPE | ISOLDE | LHS | Szafranski | |
---|---|---|---|---|---|---|---|---|
Patient, N (%) | 8686 (100) | 90 (1.0) | 231 (2.7) | 1500 (17.3) | 982 (11.3) | 260 (3.0) | 5591 (64.4) | 32 (0.4) |
Age, y (SD) | 51.9 (9.1) | 62.4 (9.4) | 58.9 (9.1) | 60.2 (9.0) | 52.5 (7.6) | 63.9 (8.0) | 48.4 (6.8) | 66.3 (8.5) |
Women, N (%) | 3229 (37.2) | 25 (27.8) | 94 (40.7) | 665 (44.3) | 276 (28.1) | 81 (31.2) | 2085 (37.3) | 3 (9) |
Current smoker, N (%) | 4849 (55.9) | 29 (32.2) | 175 (75.8) | 426 (28.7) | 982 (100) | 126 (48.5) | 3096 (55.4) | 15 (46.9) |
GOLD grade, N (%) | ||||||||
1 | 3674 (42.3) | 12 (13.3) | 105 (45.5) | 575 (38.3) | 354 (36.0) | 9 (3.5) | 2619 (46.8) | 0 (0) |
2 | 5012 (57.7) | 78 (86.7) | 126 (54.5) | 925 (61.7) | 628 (64.0) | 251 (96.5) | 2972 (53.2) | 32 (100) |
FEV1 | ||||||||
Absolute, Litre | 2.62 (0.73) | 1.84 (0.48) | 2.54 (0.80) | 2.35 (0.96) | 2.60 (0.62) | 1.83 (0.44) | 2.75 (0.63) | 1.62 (0.29) |
% predicted | 77.8 (14.4) | 63.7 (13.5) | 79.6 (15.6) | 81.6 (25.6) | 74.6 (11.6) | 61.9 (8.6) | 78.4 (9.1) | 56.0 (6.0) |
BMI, kg/m2 | 25.7 (4.3) | 25.9 (5.3) | 25.5 (4.2) | 27.3 (5.4) | 24.5 (3.3) | 25.2 (4.3) | 25.5 (3.9) | 26.0 (5.3) |
BMI category, N (%) | ||||||||
Underweight (BMI < 18.5) | 163 (1.9) | 5 (5.6) | 3 (1.3) | 30 (2.0) | 21 (2.1) | 13 (5.0) | 90 (1.6) | 1 (3.1) |
Normal (BMI 18.5–25.0) | 3945 (45.4) | 41 (45.6) | 118 (50.1) | 510 (34.0) | 555 (56.5) | 118 (45.4) | 2589 (46.3) | 14 (43.8) |
Overweight (BMI 25.1–30.0) | 3340 (38.5) | 27 (30.0) | 71 (30.7) | 589 (39.3) | 354 (30.0) | 93 (35.8) | 2194 (39.2) | 12 (37.5) |
Obese (BMI > 30.1) | 1238 (14.3) | 17 (18.9) | 39 (16.9) | 371 (24.7) | 52 (5.3) | 36 (13.8) | 718 (12.8) | 5 (15.6) |
Follow-up, mo | 36 (median) |