Fig. 3
From: MicroRNA 219-5p inhibits alveolarization by reducing platelet derived growth factor receptor-alpha
Expression of miR-219-5p (miR-219) and PDGFR-α in MLE12 and primary lung fibroblasts exposed to air or hyperoxia and treated with either mimic miR-219 or locked nucleic acid (LNA)-miR-219 inhibitor. a, b: miR-219 was increased while PDGFR-α was decreased in MLE12 and primary lung fibroblasts exposed to hyperoxia for 24 h, compared with normoxia. c, d Representative graphs showing significant decrease of PDGFR-α in mimic miR-219 transfected group and increase of PDGFR-α in LNA-miR-219 inhibitor transfected group compared to its control in both MLE12 and primary lung fibroblasts. Values are means ± SE; *P ˂ 0.05 vs. corresponding group