Fig. 1
From: S100A9 blockade prevents lipopolysaccharide-induced lung injury via suppressing the NLRP3 pathway
Effects of LPS on lung injury and S100A9 expression in mice. Mice were treated with LPS (5 mg/kg) and the lung tissues and BALF were collected at 4, 12 and 24 h following LPS treatment. a LPS induced lung injury starting at 4 h. b The protein expression levels of S100A9 in the lung tissues of mice are shown. The semi-quantified results of S100A9 expression are also shown. c The concentration of S100A9 in BALF is presented. d The concentration of S100A9 in lung homogenates is presented. Data are expressed as the mean ± SEM (n = 6 for each group). Statistical analysis was performed using two-way ANOVA followed by Tukey's multiple comparison test. **P < 0.01 vs. the corresponding control. LPS lipopolysaccharide, S100A9 S100 calcium binding protein A9, BALF bronchoalveolar lavage fluids