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Fig. 6 | Respiratory Research

Fig. 6

From: AITC inhibits fibroblast-myofibroblast transition via TRPA1-independent MAPK and NRF2/HO-1 pathways and reverses corticosteroids insensitivity in human lung fibroblasts

Fig. 6

Effect of AITC, HC-030031, ERK1/2 and NRF2 inhibition on HO-1 and α-SMA expressions after TGF-β1 stimulation. Western blot analysis of HO-1 protein expression after treatment with a AITC (10 μM) or AITC (10 μM) + HC-030031 (10 μM), (B) U0126, ERK1/2 inhibitor (10 μM) for 24 h during TGF-β1 stimulation. c Western blot analysis of α-SMA protein expression after treatment with U0126 and/or ML385, NRF2 inhibitor (10 μM) for 24 h during TGF-β1 stimulation. (*P < 0.05, * without bar; compared with the respective control). N = 3

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Respiratory Research

ISSN: 1465-993X

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