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Table 2 Inflammatory characteristics of asthmatics according to the presence of IgG and IgA against Chlamydia pneumonia

From: Chronic infection with Chlamydia pneumoniae in asthma: a type-2 low infection related phenotype

 

Chlamydia pn

IgA−, IgG−

Chlamydia pn

IgA−, IgG + 

Chlamydia pn

IgA + , IgG + 

N

145 (35.5%)

193 (47.5%)

68 (17%)

FeNO (ppb)

23 (16–47)

22 (12–38)

21 (14.3–34)

Blood eosino, %

2.7 (1.5–4.4)

2.5 (1.3–4.5)

2.9 (1.7–4)

Blood eosino, /mm3

187 (104–399)

181 (92–330)

191.5 (107–272)

Blood neutro, %

55.8 (49.4–62.2)

56 (48.2–62.1)

55.1 (49.2–62.1)

Blood neutro, /mm3

3881 (3291–4865)

3931 (3028–5358)

3959 (3162–4995)

Blood mono, %

7.1 (5.9–8.1)

7.7 (6.4–9.2)*

7.2 (5.8–9)

Blood mono, /mm3

492 (390–647)

572 (444–707)*

514 (401–644)

Blood lympho, %

33 (27.7–38.4)

32.2 (25.7–39.2)

32.6 (25.9–41.1)

Blood lympho, /mm3

2360 (1878–2839)

2298 (1888–2787)

2201 (1780–2777)

IgE (U/L)

74 (28–259.5)

97.5 (26.5–315)

85.5 (28–284)

Fibrinogen, g/l

3.28 (2.66–3.81)

3.32 (2.76–3.84)

3.5 (3.03–3.98)*

CRP, mg/l

2.14 (0.84–5.39)

2.53 (0.99–5.14)

2.47 (1.07–4.86)

Alpha-1-antitrypsin

1.37 (1.21–1.54)

1.43 (1.29–1.58)*

1.47 (1.31–1.58)

Cortisol, nmol/l

175 (138–295)

187 (146–271)

183 (125–268)

Sputum eosino, %

2.1 (0.35–9.6)

1.2 (0.2–4.9)

0.8 (0–3.5)*

Sputum eosino, × 103/gr

45 (2.1–170.3)

16 (0.74–116)

12.1 (0–64.4)*

Sputum neutro, %

61 (44.5–80.4)

63.6 (42.2–83.6)

69.9 (35.5–83.8)

Sputum neutro, × 103/gr

906 (350–2405)

878 (304–3543)

811.5 (294–2292)

Sputum lympho, %

1 (0.2–1.95)

1 (0.2–2)

0.8 (0–1.9)

Sputum lympho, × 103/gr

11.8 (1.65–37.7)

14.4 (2–47.3)

10.1 (0–36.7)

Sputum macro, %

20.5 (10.6–35.4)

20.3 (9.7–36.5)

17.6 (10.3–36.6)

Sputum macro, × 103/gr

311 (123–665)

363 (139–839)

263 (115–846)

  1. Results are presented as mean + SD for categorial variables and median (IQR) for skewed distribution. *:  Significantly different from IgA−IgG−group
  2. *: Different from IgA−/IgG−. #: different from IgA−IgG + 
  3. *p < 0.05
  4. **p < 0.001
  5. ***p < 0.0001
  6. # p < 0.05
  7. ## p < 0.001
  8. ### p < 0.0001