Baseline characteristics and survival of patients of idiopathic pulmonary fibrosis: a longitudinal analysis of the Swedish IPF Registry

Table 2 Univariable Cox analysis for survival

Variable	n	HR	95% CI	p-value
Age, years, at enrolment into the registry	480	1.027	1.006–1.049	0.012
Male versus female	480	1.373	0.973–1.936	0.071
BMI, per kg·m²	450	0.948	0.911–0.986	0.008
Ex/current smoker versus never-smoker	480	1.43	1.052–1.944	0.023
CCI index	480	1.039	0.944–1.144	0.435
Comorbidities number	480	0.989	0.881–1.109	0.848
Heart diseases	480	1.134	0.842–1.529	0.407
Acid reflux	480	0.760	0.550–1.050	0.096
FVC % predicted	385	0.972	0.962–0.983	< 0.001
DLCO % predicted	310	0.957	0.943–0.971	< 0.001
TLC % predicted	282	0.952	0.936–0.969	< 0.001
CPI	282	1.064	1.043–1.085	< 0.001
GAP stage	290	1.943	1.448–2.607	< 0.001
6MWD, m	284	0.996	0.995–0.998	< 0.001
LpSO2, %	284	0.934	0.904–0.965	< 0.001
K-BILD	317	0.965	0.947–0.983	< 0.001

IPF Idiopathic pulmonary fibrosis, HR hazard ratios, BMI Body mass index, CCI Charlson Comorbidity Index, FVC Forced vital capacity, DLCO Diffusing capacity of carbon monoxide, TLC total lung capacity, CPI composite physiological index, GAP gender-age-physiology index for IPF, K-BIL King's brief interstitial lung disease health status questionnaire, 6MWD 6-min walking distance during 6MWT, L-SpO₂ Lowest oxygen saturation during 6MWT

ISSN: 1465-993X