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Fig. 2 | Respiratory Research

Fig. 2

From: LncRNA SNHG16 promotes pulmonary fibrosis by targeting miR-455-3p to regulate the Notch2 pathway

Fig. 2

Knockdown of SNHG16 attenuated BLM-induced pulmonary fibrosis. a The timelines of both groups were shown. b The expression level of SNHG16 were measured by qRT-PCR in saline or BLM injected mice which treated with shRNAs targeted SNHG16 (shSNHG16#1, shSNHG16#2). c, d HE and Massion staining were performed on lung tissues (saline or BLM injected) with sh-SNHG16 treated or its control (sh-NC). e The expression level of protein α-SMA, E-cadherin, collagen 1 and fibronectin 1 in BLM injected or saline injected group with or without knockdown of SNHG16 were determined by western blot. Data were expressed as mean ± SD. **P < 0.01 vs Ad sh-NC Saline, ##P < 0.01 vs Ad sh-NC BLM, represent statistically difference

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