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Table 1 Demographic and clinical characteristics of the 41 patients that died due to COVID-19

From: Tracking the time course of pathological patterns of lung injury in severe COVID-19

Female/male 18/23
Caucasians, n (%) 35 (85%)
Age in years, median (range) 55 (22—88)
Body mass index, median (range) 26 (13—48)
Comorbidities, n (%)
Diabetes 13 (32.5%)
Systemic arterial hypertension 20 (50%)
Cardiomyopathy 10 (25%)
Vascular disase 5 (12.5%)
Chronic kidney disease 4 (10%)
Asthma 2 (5%)
Chronic obstructive pulmonary disease 5 (12.5%)
Smoker 4 (10%)
Comorbidities number  
 1 20 (54.1%)
 2 10 (27%)
 3 2 (5.4%)
 4 3 (8.1%)
 5 2 (5.4%)
Symptoms, n (%)
Fever 29 (72.5%)
Dyspnoea 33 (82.5%)
Cough 27 (67.5%)
Rhinorrhea 6 (15%)
Diarrhoea 9 (22.5%)
Myalgia 14 (35%)
Sore throat 5 (12.5%)
Nausea and vomiting 10 (25%)
Others 15 (37.5%)
Use of corticosteroids, n (%) 23 (57.5%)
Use of anticoagulants, n (%) 11 (30.8%)
Use of vasoactive drugs (admission), n = 37 15 (40.5%)
Use of mechanical ventilation, n = 37 37 (100%)
Prone positioning, n = 37 12 (32.4%)
Extracorporeal membrane oxygenation, n = 37 4 (10.8%)
Dialysis, n = 37 20 (54.1%)
Glasgow coma scale (day 1), n = 37 3 (3–15)
Simplified acute physiology score III (day 1), n = 37 66 (39–97)
Laboratory parameters from 24 h before death, median (range)
D Dimer (ng/ml), n = 32 4593 (815–126,078)
Fibrinogen (mg/dl), n = 20 485.5 (89–2465)
Platelets (ml/mm3), n = 39 158,000 (4000–322,000)
Activated partial thromboplastin time (s), n = 32 1.23 (0.92–7.0)
Lymphocytes (ml/mm3), n = 39 0.37 (0.04–1.05)
Lung parameters from 24 h before death, median (range)
PEEP (cmH2O), n = 35 10 (5–20)
FiO2 (%), n = 35 60 (25–100)
PaO2/FiO2 ratio, n = 28 122.5 (56–430)
Time from symptom onset to hospitalization in days, median (range) 5 (0–26)
Time from symptom onset to death in days, median (range) 18 (3–47)
Period of hospitalisation in days, median (range) 12 (0–40)
Intensive care unit stay in days, median (range) 9 (0–38)
Period of mechanical ventilation in days, median (range) 11 (0–39)
  1. PEEP Positive end-expiratory pressure, FiO2 fraction of inspired oxygen ratio, PaO2/FiO2 ratio arterial oxygen partial pressure/inspired oxygen fraction ratio
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