Pulmonary function test, n = 22 (mean ± SD) | FEV1 (L) | 2.88 ± 0.66 |
FEV1 (%) | 89.4 ± 15.7 | |
FVC (L) | 3.38 ± 0.81 | |
FVC (%) | 83.64 ± 16.9 | |
FEV1/FCV | 0.86 ± 0.06 | |
DLCO (%) | 80.7 ± 14.3 | |
PFT interpretation | Normal Restrictive pattern Restrictive + altered diffusion Altered diffusion | n = 10 n = 2 n = 4 n = 6 |
6MWDT, n = 20 (mean ± SD) | Distance (m) | 514.4 ± 93.1 |
Distance (%) | 73.5 ± 12.3 | |
Distance < 80% | n = 13 | |
Desaturation | n = 6 | |
Respiratory muscle strength, n = 21 (mean ± SD) | MIP (cm H2O) | 85.7 ± 24.9 |
MIP (%) | 81.8 ± 15.2 | |
MIP < 80% | n = 9 | |
MEP (cm H2O) | 102.8 ± 32.3 | |
MEP (%) | 66.1 ± 30.7 | |
MEP < 80% | n = 17 | |
MMRC, n = 21, mean ± SD | 0.7 ± 1.7 | |
SF-36, n = 22 (mean ± SD) | Physical functioning | 70.79 ± 21.30 |
Role physical | 33.82 ± 37.44 | |
Pain | 64.60 ± 26.61 | |
General health | 59.90 ± 17.62 | |
Vitality | 56.84 ± 16.68 | |
Social | 69.38 ± 22.02 | |
Role emotional | 38.61 ± 48.77 | |
Mental health | 69.68 ± 16.99 | |
Chest CT Scan, n = 22 | Baseline | 3-months |
Normal | n = 0 | n = 3 |
Number of affected segments in both lungs (mean ± SD), score/20 | 17.2 ± 19 | 8.1 ± 10.1 |
Predominant abnormalities | ||
Ground glass opacities | n = 22 | n = 0 |
Consolidation | n = 16 | n = 2 |
Fibrosis | n = 9 | n = 19 |
Abnormalities distribution | ||
Peripheral location | n = 8 | n = 7 |
Diffuse location | n = 14 | n = 12 |
Lower lobes predominant involvement | n = 12 | n = 11 |