Table 2 Functional and inflammatory characteristics of patients according to the age group

n

186

468

104

FeNO, ppb

35(15–70)

27 (14–52)

22 (16–49)

Sputum eosinophils, %

1.4 (0.2–9.5)

2.5 (0.2–14.4)

2.7 (0.2–11.4)

Sputum eosinophils, AV

11.7 (0.32–96)

34.6 (4–175)*

25.3 (0.79–239)

Sputum neutrophils, %

37 (15.7–65.4)

48.4 (25–68)***

57 (29–81)^{###^^^}

Sputum neutrophils, AV

538 (213–1554)

721 (283–2292)

1160 (323–3527)^{##^^}

Sputum macrophages, %

34 (14–53)

21 (11–36)***

15 (7–25)^{###^^^}

Sputum lymphocytes, %

1 (0.2–2)

1 (0..2–2)

1 (0.2–1.8)

Sputum weight

2 (1.35–3.4)

2.32 (1.35–3.9)

2.32 (1.24–3,6)

Blood eosinophils, %

3.2 (1.7–5.8)

2.7 (1.5–4.6)

2.9 (1.9–4.8)

Blood eosinophils, /mm³

240 (145–465)

220 (120–390)

270 (143–385)

Blood neutrophils, %

55 (49–63)

57 (49–63)

60 (53–64)

Blood neutrophils, /mm³

4180 (3315–5157)

4217 (3570–5550)

4220 (3520–5440)

FEV₁, %

96 (86–100)

90 (76–104)*

84 (69–97)^{###^}

Reversibility, %

7.7 (3–15)

8 (2.7–15)

11 (3.4–18)

FVC,%

97 ( 89–108)

97 (82–111)

90 (78–101)

FEV₁/FVC, post,%

82 (77–86)

77 (70–83)**

76 (69–82)^##

TLC, %

96 (89–104)

100 (91–112)

102 (96–114)

FRC, %

101

104

106

RV/TLC, %

29 (24–35)

44 (36–51)***

53 (45–60)^{####^^^^}

DLCO, %

78

76

69^{#^}

KCO, %

93

90

95

sGaw, kPa/sec

0.84 (0.65–1.1)

0.8 (0.6–1.1)

0.7 (0.5–1)^{##^^}

PC20M mg/ml

2 (0.5–7.2)

3,7 (1.17–15)*

8,8 (1.7–16)^#

IgE, kU/l

330 (107–624)

112 (46–324)****

83 (29–380)^{####^^^^}

RAST HDM

2.3 (0.3–25.4)

0.3 (0.1–1)***

0.3 (0.1–0.3)^####

RAST birch

0.3 (0–4.4)

0.3 (0.1–0.3)*

0.3 (0.1–0.3)^###

RAST cat

0.7 (0.1–14)

0.3 (0–0.5)*

0.3 (0–0.3)^###

RAST dog

0.3 (0.1–2.7)

0.3 (0–0.3)*

0.3 (0–0.3)^###

RAST grass pollen

2.8 (0.3–25)

0.3 (0.1–0.5)***

0.3 (0.1–0.3)^###

RAST moulds

0.29 (0.1–0.3)

0.1 (0–0.3)

0.3 (0–0.3)

CRP, mg/l

1.5 (0.6–3.5)

1.75 (0.8–4)

2.3 (1.1–4.5)

Fibrinogen, g/l

2,9 (2.5–3.2)

3,1 (2.8–3.8)**

3,5 (3.2–4.3)^{##^^}