Table 1 Demographic characteristics of patients according to the age group
< 40 years | 40–70 | ≥ 70 | Global p-value | |
|---|---|---|---|---|
n | 186 | 468 | 104 | |
Gender (M/F) | 73/113 (39%) | 180/289 (38%) | 47/57 (45%) | > 0.05 |
Weight, kg | 69 (58–79) | 74 (63–86)*** | 71 (62–86)### | 0.0002 |
Height, cm | 168 (161–176) | 167 (162–175) | 164 (158–170)#^ | 0.000004 |
BMI, kg/m2 | 22.8 (15–41) | 26.4 (16–42)*** | 27 (18–37)###^^^ | 0.000001 |
Smokers | 20% | 23% | 8%###^^^ | |
Pack-yr | 0 (0–25) | 0 (0–45)*** | 0 (0–50) ## | 0.000001 |
ACQ | 1.7 (1–2.57) | 1.9 (1–3) | 1,9 (1–3,86) | > 0.05 |
AQLQ | 4.9 (3.9–5.97) | 4.5 (3.5–5.6)* | 5 (3.8–5.9)#^ | 0.001 |
Emotional trigger | 5.2 (1–7) | 4.4 (1–7)** | 5.4 (2–7)^^ | 0.019 |
Environmental stimulus | 4.8 (1–7) | 4.5 (1–7) | 4.8 (1.3–7) | > 0.05 |
Symptoms | 4.8 (1.2–7) | 4.3 (1.2–7) | 5 (1.8–7) | 0.006 |
Age of onset | 15 (5–25) | 35 (15–50)*** | 55 (32–68)###^^^ | 0.000001 |
Duration of asthma | 11 (1–19) | 13 (2–35)*** | 15 (3–40)### | 0.0013 |
ICS | 400 (0–1000) | 500 (0–1000) | 500 (0–1000) | > 0.05 |
LABA, % | 58 | 63 | 64 | > 0.05 |
LAMA, % | 0,6 | 5** | 8## | 0.001 |
Anti-leukotrienes (%) | 25 | 25 | 33 | > 0.05 |
Anti-IL5 (n) | 0 | 5 | 1 | > 0.05 |
Exacerbations (n) | 0 (0–7) | 0 (0–10) | 0 (0–6) | > 0.05 |