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Table 2 Baseline characterization of COPD patients who achieved 10 years of follow-up and those who died

From: Telomere length dynamics over 10-years and related outcomes in patients with COPD

Variable

Total patients included (n = 134)

Alive after 10 year-follow-up (n = 42)

Died during 10 year-follow-up (n = 43)

p-value

Age

64 9

61 ± 8

69 ± 9

0.001

BMIa

27 ± 5

27 ± 6

28 ± 5

0.781

Smoking habit (pack-year)a,c

65 ± 26

61 ± 22

70 ± 31

0.139

Active smoking (%)

43

52

33

0.069

FEV1 (L)a

1.52 ± 0.62

1.61 ± 0.61

1.34 ± 0.56

0.038

FEV1 (% pred)a

58 ± 21

61 ± 19

51 ± 21

0.027

FVC (% pred)a

89 ± 24

90 ± 23

81 ± 25

0.070

FEV1/FVC (% pred)a

51 ± 11

54 ± 10

49 ± 11

0.024

PaO2a

72 ± 11

73 ± 10

68 ± 10

0.015

KCOa

80 ± 26

90 ± 28

74 ± 23

0.009

IC/TLC (%)a

34 ± 8

35 ± 8

33 ± 8

0.143

6MWD (mts)a

495 ± 90

522 ± 83

474 ± 75

0.008

mMRC dysneab

1 (0–2)

1 (0–1)

1 (0–2)

0.703

BODE indexb

1 (0–3)

1 (0–2)

1 (0–3)

0.179

Charlson indexb

0 (0–1)

0 (0–1)

1 (0–1)

0.740

  1. Paired sample t test was used
  2. BMI body mass index, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, % pred per cent predicted, PaO2 partial oxygen tension, KCO transfer factor coefficient of the lung for carbon monoxide, which is DLCO, IC/TLC inspiratory capacity to total lung capacity ratio, SMWD 6 min walking distance test
  3. p-value between compared groups
  4. aData are presented as mean ± SD
  5. bData are presented as median (25th–75th pc)
  6. cNumber of packs of cigarettes smoked per day × number of years smoking