TY - STD TI - Singh D, Agusti A, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease: the GOLD science committee report 2019. Eur Respir J. 2019;53(5). ID - ref1 ER - TY - JOUR AU - Lipson, D. A. AU - Barnhart, F. AU - Brealey, N. AU - Brooks, J. AU - Criner, G. J. AU - Day, N. C. PY - 2018 DA - 2018// TI - Once-daily single-inhaler triple versus dual therapy in patients with COPD JO - N Engl J Med VL - 378 UR - https://doi.org/10.1056/NEJMoa1713901 DO - 10.1056/NEJMoa1713901 ID - Lipson2018 ER - TY - STD TI - Cazzola M, Rogliani P, Calzetta L, Matera MG. Triple therapy versus single and dual long-acting bronchodilator therapy in COPD: a systematic review and meta-analysis. Eur Respir J. 2018; 52(6). ID - ref3 ER - TY - STD TI - Roche N, Anzueto A, Bosnic Anticevich S, Kaplan A, Miravitlles M, Ryan D, et al. Connected real-life research, a pillar of P4 medicine. Eur Respir J. 2020; 55(1). ID - ref4 ER - TY - JOUR AU - Voorham, J. AU - Corradi, M. AU - Papi, A. AU - Vogelmeier, C. F. AU - Singh, D. AU - Fabbri, L. M. PY - 2019 DA - 2019// TI - Comparative effectiveness of triple therapy versus dual bronchodilation in COPD JO - ERJ Open Res VL - 5 UR - https://doi.org/10.1183/23120541.00106-2019 DO - 10.1183/23120541.00106-2019 ID - Voorham2019 ER - TY - JOUR AU - Grewe, F. A. AU - Sievi, N. A. AU - Bradicich, M. AU - Roeder, M. AU - Brack, T. AU - Brutsche, M. H. PY - 2020 DA - 2020// TI - Compliance of pharmacotherapy with GOLD guidelines: a longitudinal study in patients with COPD JO - Int J Chron Obstruct Pulmon Dis VL - 15 UR - https://doi.org/10.2147/COPD.S240444 DO - 10.2147/COPD.S240444 ID - Grewe2020 ER - TY - JOUR AU - Halpin, D. M. G. AU - Jong, H. J. I. AU - Carter, V. AU - Skinner, D. AU - Price, D. PY - 2019 DA - 2019// TI - Distribution, temporal stability and appropriateness of therapy of patients with COPD in the UK in relation to GOLD 2019 JO - EClinicalMedicine VL - 14 UR - https://doi.org/10.1016/j.eclinm.2019.07.003 DO - 10.1016/j.eclinm.2019.07.003 ID - Halpin2019 ER - TY - JOUR AU - Barrecheguren, M. AU - Monteagudo, M. AU - Ferrer, J. AU - Borrell, E. AU - Llor, C. AU - Esquinas, C. PY - 2016 DA - 2016// TI - Treatment patterns in COPD patients newly diagnosed in primary care. A population-based study JO - Respir Med VL - 111 UR - https://doi.org/10.1016/j.rmed.2015.12.004 DO - 10.1016/j.rmed.2015.12.004 ID - Barrecheguren2016 ER - TY - JOUR AU - Calle Rubio, M. AU - Rodríguez Hermosa, J. L. AU - Soler-Cataluña, J. J. AU - López-Campos, J. L. AU - Alcazar Navarrete, B. AU - Soriano, J. B. PY - 2018 DA - 2018// TI - Medical care according to risk level and adaptation to Spanish COPD guidelines (GesEPOC): the Epoconsul study JO - Arch Bronconeumol VL - 54 UR - https://doi.org/10.1016/j.arbres.2017.11.015 DO - 10.1016/j.arbres.2017.11.015 ID - Calle Rubio2018 ER - TY - JOUR AU - Miravitlles, M. AU - Cosio, B. G. AU - Arnedillo, A. AU - Calle, M. AU - Alcazar-Navarrete, B. AU - Gonzalez, C. PY - 2017 DA - 2017// TI - A proposal for the withdrawal of inhaled corticosteroids in the clinical practice of chronic obstructive pulmonary disease JO - Respir Res VL - 18 UR - https://doi.org/10.1186/s12931-017-0682-y DO - 10.1186/s12931-017-0682-y ID - Miravitlles2017 ER - TY - JOUR AU - Avdeev, S. AU - Aisanov, Z. AU - Arkhipov, V. AU - Belevskiy, A. AU - Leshchenko, I. AU - Ovcharenko, S. PY - 2019 DA - 2019// TI - Withdrawal of inhaled corticosteroids in COPD patients: rationale and algorithms JO - Int J Chron Obstruct Pulmon Dis VL - 14 UR - https://doi.org/10.2147/COPD.S207775 DO - 10.2147/COPD.S207775 ID - Avdeev2019 ER - TY - JOUR AU - Micheletto, C. AU - Braido, F. AU - Contoli, M. AU - Marco, F. AU - Santus, P. PY - 2019 DA - 2019// TI - A framework for step down or therapeutic re-organization for withdrawal of inhaled corticosteroids in selected patients with COPD: a proposal for COPD management JO - Int J Chron Obstruct Pulmon Dis VL - 14 UR - https://doi.org/10.2147/COPD.S216059 DO - 10.2147/COPD.S216059 ID - Micheletto2019 ER - TY - JOUR AU - Kaplan, A. G. PY - 2015 DA - 2015// TI - Applying the wisdom of stepping down inhaled corticosteroids in patients with COPD: a proposed algorithm for clinical practice JO - Int J Chron Obstruct Pulmon Dis VL - 10 UR - https://doi.org/10.2147/COPD.S93321 DO - 10.2147/COPD.S93321 ID - Kaplan2015 ER - TY - JOUR AU - Nici, L. AU - Mammen, M. J. AU - Charbek, E. AU - Alexander, P. E. AU - Au, D. H. AU - Boyd, C. M. PY - 2020 DA - 2020// TI - Pharmacologic management of chronic obstructive pulmonary disease. An official American Thoracic Society clinical practice guideline JO - Am J Respir Crit Care Med VL - 201 UR - https://doi.org/10.1164/rccm.202003-0625ST DO - 10.1164/rccm.202003-0625ST ID - Nici2020 ER - TY - STD TI - Chalmers JD, Laska IF, Franssen FME, Janssens W, Pavord I, Rigau D, et al. Withdrawal of inhaled corticosteroids in chronic obstructive pulmonary disease: a European Respiratory Society guideline. Eur Respir J. 2020; 55 ID - ref15 ER - TY - JOUR AU - D’Urzo, A. AU - Donohue, J. F. AU - Kardos, P. AU - Miravitlles, M. AU - Price, D. PY - 2015 DA - 2015// TI - A re-evaluation of the role of inhaled corticosteroids in the management of patients with chronic obstructive pulmonary disease JO - Expert Opin Pharmacother VL - 16 UR - https://doi.org/10.1517/14656566.2015.1067682 DO - 10.1517/14656566.2015.1067682 ID - D’Urzo2015 ER - TY - JOUR AU - Hurst, J. R. AU - Vestbo, J. AU - Anzueto, A. AU - Locantore, N. AU - Müllerova, H. AU - Tal-Singer, R. PY - 2010 DA - 2010// TI - Susceptibility to exacerbation in chronic obstructive pulmonary disease JO - N Engl J Med VL - 363 UR - https://doi.org/10.1056/NEJMoa0909883 DO - 10.1056/NEJMoa0909883 ID - Hurst2010 ER - TY - JOUR AU - Izquierdo, J. L. AU - Morena, D. AU - González, Y. AU - Paredero, J. M. AU - Pérez, B. AU - Graziani, D. AU - Gutiérrez, M. AU - Rodríguez, J. M. PY - 2020 DA - 2020// TI - Clinical management of COPD in a real-world setting. A Big Data analysis JO - Arch Bronconeumol. UR - https://doi.org/10.1016/j.arbres.2019.12.025 DO - 10.1016/j.arbres.2019.12.025 ID - Izquierdo2020 ER - TY - JOUR AU - Miravitlles, M. AU - Monteagudo, M. AU - Solntseva, I. AU - Alcázar, B. PY - 2021 DA - 2021// TI - Blood eosinophil counts and their variability and risk of exacerbations in COPD: a population-based study JO - Arch Bronconeumol VL - 57 UR - https://doi.org/10.1016/j.arbres.2019.12.015 DO - 10.1016/j.arbres.2019.12.015 ID - Miravitlles2021 ER - TY - JOUR AU - Chalmers, J. D. AU - Poole, C. AU - Webster, S. AU - Tebboth, A. AU - Dickinson, S. AU - Gayle, A. PY - 2018 DA - 2018// TI - Assessing the healthcare resource use associated with inappropriate prescribing of inhaled corticosteroids for people with chronic obstructive pulmonary disease (COPD) in GOLD groups A or B: an observational study using the Clinical Practice Research Data JO - Respir Res VL - 19 UR - https://doi.org/10.1186/s12931-018-0767-2 DO - 10.1186/s12931-018-0767-2 ID - Chalmers2018 ER - TY - JOUR AU - Cataldo, D. AU - Derom, E. AU - Liistro, G. AU - Marchand, E. AU - Ninane, V. AU - Peche, R. PY - 2018 DA - 2018// TI - Overuse of inhaled corticosteroids in COPD: five questions for withdrawal in daily practice JO - Int J Chron Obstruct Pulmon Dis VL - 13 UR - https://doi.org/10.2147/COPD.S164259 DO - 10.2147/COPD.S164259 ID - Cataldo2018 ER - TY - JOUR AU - Nadeem, N. J. AU - Taylor, S. J. C. AU - Eldridge, S. M. PY - 2011 DA - 2011// TI - Withdrawal of inhaled corticosteroids in individuals with COPD—a systematic review and comment on trial methodology JO - Respir Res VL - 12 UR - https://doi.org/10.1186/1465-9921-12-107 DO - 10.1186/1465-9921-12-107 ID - Nadeem2011 ER - TY - JOUR AU - Magnussen, H. AU - Disse, B. AU - Rodriguez-Roisin, R. AU - Kirsten, A. AU - Watz, H. AU - Tetzlaff, K. PY - 2014 DA - 2014// TI - Withdrawal of inhaled glucocorticoids and exacerbations of COPD JO - N Engl J Med VL - 371 UR - https://doi.org/10.1056/NEJMoa1407154 DO - 10.1056/NEJMoa1407154 ID - Magnussen2014 ER - TY - JOUR AU - Magnussen, H. AU - Tetzlaff, K. AU - Bateman, E. D. AU - Watz, H. AU - Kirsten, A. M. AU - Wouters, E. F. PY - 2016 DA - 2016// TI - Lung function changes over time following withdrawal of inhaled corticosteroids in patients with severe COPD JO - Eur Respir J VL - 47 UR - https://doi.org/10.1183/13993003.01644-2015 DO - 10.1183/13993003.01644-2015 ID - Magnussen2016 ER - TY - JOUR AU - Watz, H. AU - Tetzlaff, K. AU - Wouters, E. F. M. AU - Kirsten, A. AU - Magnussen, H. AU - Rodriguez-Roisin, R. PY - 2016 DA - 2016// TI - Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the WISDOM trial JO - Lancet Respir Med VL - 4 UR - https://doi.org/10.1016/S2213-2600(16)00100-4 DO - 10.1016/S2213-2600(16)00100-4 ID - Watz2016 ER - TY - JOUR AU - Chapman, K. R. AU - Hurst, J. R. AU - Frent, S. -. M. AU - Larbig, M. AU - Fogel, R. AU - Guerin, T. PY - 2018 DA - 2018// TI - Long-term triple therapy de-escalation to indacaterol/glycopyrronium in patients with chronic obstructive pulmonary disease (SUNSET): a randomized, double-blind, triple-dummy clinical trial JO - Am J Respir Crit Care Med VL - 198 UR - https://doi.org/10.1164/rccm.201803-0405OC DO - 10.1164/rccm.201803-0405OC ID - Chapman2018 ER - TY - JOUR AU - Rossi, A. AU - Guerriero, M. AU - Corrado, A. PY - 2014 DA - 2014// TI - Withdrawal of inhaled corticosteroids can be safe in COPD patients at low risk of exacerbation: a real-life study on the appropriateness of treatment in moderate COPD patients (OPTIMO) JO - Respir Res VL - 15 UR - https://doi.org/10.1186/1465-9921-15-77 DO - 10.1186/1465-9921-15-77 ID - Rossi2014 ER - TY - JOUR AU - Vogelmeier, C. AU - Worth, H. AU - Buhl, R. AU - Criée, C. P. AU - Lossi, N. S. AU - Mailänder, C. PY - 2017 DA - 2017// TI - "Real-life" inhaled corticosteroid withdrawal in COPD: a subgroup analysis of DACCORD JO - Int J Chron Obstruct Pulmon Dis VL - 12 UR - https://doi.org/10.2147/COPD.S125616 DO - 10.2147/COPD.S125616 ID - Vogelmeier2017 ER - TY - JOUR AU - Oshagbemi, O. A. AU - Franssen, F. M. E. AU - Kraaij, S. AU - Braeken, D. C. W. AU - Wouters, E. F. M. AU - Maitland-van der Zee, A. H. PY - 2019 DA - 2019// TI - Blood eosinophil counts, withdrawal of inhaled corticosteroids and risk of COPD exacerbations and mortality in the clinical practice research datalink (CPRD) JO - COPD VL - 16 UR - https://doi.org/10.1080/15412555.2019.1608172 DO - 10.1080/15412555.2019.1608172 ID - Oshagbemi2019 ER - TY - JOUR AU - Jo, T. AU - Yasunaga, H. AU - Yamauchi, Y. AU - Mitani, A. AU - Hiraishi, Y. AU - Hasegawa, W. PY - 2020 DA - 2020// TI - Inhaled corticosteroid withdrawal may improve outcomes in elderly patients with COPD exacerbation: a nationwide database study JO - ERJ Open Res VL - 6 UR - https://doi.org/10.1183/23120541.00246-2019 DO - 10.1183/23120541.00246-2019 ID - Jo2020 ER - TY - JOUR AU - Harries, T. H. AU - Gilworth, G. AU - Corrigan, C. J. AU - Murphy, P. B. AU - Hart, N. AU - Thomas, M. PY - 2019 DA - 2019// TI - Inhaled corticosteroids prescribed for COPD patients with mild or moderate airflow limitation: who warrants a trial of withdrawal? JO - Int J Chron Obstruct Pulmon Dis VL - 14 UR - https://doi.org/10.2147/COPD.S238239 DO - 10.2147/COPD.S238239 ID - Harries2019 ER - TY - JOUR AU - López-Campos, J. L. AU - Carrasco-Hernández, L. AU - Román Rodríguez, L. AU - Quintana-Gallego, E. AU - Carmona Bernal, C. AU - Alcázar, N. B. PY - 2020 DA - 2020// TI - The clinical implications of triple therapy in fixed-dose combination in COPD: from the trial to the patient JO - Arch Bronconeumol VL - 56 UR - https://doi.org/10.1016/j.arbres.2019.11.011 DO - 10.1016/j.arbres.2019.11.011 ID - López-Campos2020 ER - TY - JOUR AU - Bloom, C. I. AU - Douglas, I. AU - Usmani, O. S. AU - Quint, J. K. PY - 2020 DA - 2020// TI - Inhaled corticosteroid treatment regimens and health outcomes in a UK COPD population study JO - Int J Chron Obstruct Pulmon Dis VL - 15 UR - https://doi.org/10.2147/COPD.S241568 DO - 10.2147/COPD.S241568 ID - Bloom2020 ER - TY - JOUR AU - Monteagudo, M. AU - Nuñez, A. AU - Solntseva, I. AU - Dhalwani, N. AU - Booth, A. AU - Barrecheguren, M. PY - 2020 DA - 2020// TI - Treatment pathways before and after triple therapy in COPD: a population-based study in Primary Care in Spain JO - Arch Bronconeumol UR - https://doi.org/10.1016/j.arbres.2020.07.032 DO - 10.1016/j.arbres.2020.07.032 ID - Monteagudo2020 ER - TY - JOUR AU - Lee, S. H. AU - Lee, J. H. AU - Yoon, H. I. AU - Park, H. Y. AU - Kim, T. H. AU - Yoo, K. H. PY - 2019 DA - 2019// TI - Change in inhaled corticosteroid treatment and COPD exacerbations: an analysis of real-world data from the KOLD/KOCOSS cohorts JO - Respir Res VL - 20 UR - https://doi.org/10.1186/s12931-019-1029-7 DO - 10.1186/s12931-019-1029-7 ID - Lee2019 ER - TY - JOUR AU - Suissa, S. AU - Coulombe, J. AU - Ernst, P. PY - 2015 DA - 2015// TI - Discontinuation of inhaled corticosteroids in COPD and the risk reduction of pneumonia JO - Chest VL - 148 UR - https://doi.org/10.1378/chest.15-0627 DO - 10.1378/chest.15-0627 ID - Suissa2015 ER -