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Fig. 7 | Respiratory Research

Fig. 7

From: Mesenchymal stromal cell-derived exosomes improve pulmonary hypertension through inhibition of pulmonary vascular remodeling

Fig. 7

Effect of MSC-exo on hypoxia-induced PAEC angiogenesis, migration, EndMT and adhesion ability. a Tube formation on Matrigel-coated plates. b Immunofluorescence analysis of CD31, a-SMA and VE-Cadherin using a light microscope at a × 400 magnification. b. Transwell assays to observe migratory ability at a × 200 magnification. c Protein expression and comparative analysis of of CD31 and a-SMA (d) Protein expression and comparative analysis of RhoA in PAECs by Western blot. n = 3 times repeated; P < 0.05, one-way ANOVA followed by post hoc test; the data are present as mean ± SD; *hypoxia or *MSC-CM vs. control; #MSC-exo vs. hypoxia group; * si Wnt5a vs. MSC-exo group. Scale bar = 100 μm

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