Table 1 Baseline demographics and disease characteristics
Parameter | Analysed patients (N = 54) |
|---|---|
Age (years), mean (SD) | 65.6 (5.9) |
Male gender, n (%) | 38 (70) |
Race, n (%) | |
 Caucasian | 53 (98) |
 Asian | 1 (2) |
BMI (kg/m2), mean (SD) | 26.2 (4.5) |
Time since first COPD diagnosis (years), mean (SD) | 9.3 (4.7) |
Smoking status at screening, n (%) | |
 Ex-smoker | 24 (44) |
 Current smoker | 30 (56) |
Post-bronchodilator FEV1 (L), mean (SD) | 1.46 (0.43) |
Post-bronchodilator FEV1 (% predicted), mean (SD) | 50.1 (11.7) |
 30 to < 50% predicted, n (%) | 26 (48) |
 50 to 70% predicted, n (%) | 28 (52) |
COPD Assessment Test, mean (SD) | 20.4 (6.0) |
Sputum characteristics, mean (SD) | |
 Total cell count (× 106/g) | 4.6 (5.9) |
 Neutrophil % | 82.4 (9.0) |
 Macrophage % | 11.1 (7.5) |
 Eosinophil % | 3.9 (4.4) |
 Lymphocyte % | 0.2 (0.3) |
 Epithelial cells % | 2.5 (3.7) |