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Fig. 1 | Respiratory Research

Fig. 1

From: Melatonin receptor agonist protects against acute lung injury induced by ventilator through up-regulation of IL-10 production

Fig. 1

Effect of melatonin and ramelteon on lung edema. VILI significantly increased the lung weight/body weight ratio (a), W/D weight ratio (b), and protein levels in BALF (c). Melatonin or ramelteon treatment significantly reduced these increases. The protective effect of melatonin and ramelteon was abrogated by luzindole treatment. The data are expressed as the mean ± SD (n = 6 per group). *Significantly different from the control (p-values < 0.05); #significantly different from the VILI group (p < 0.05)

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