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Table 2 Main general, functional and flow cytometric data of groups of COPD patients

From: Adaptive NKG2C+ natural killer cells are related to exacerbations and nutritional abnormalities in COPD patients

 nNKG2C+ < 20%NKG2C+ > 20%Significance
Age (years)6671 ± 867 ± 9ns
Sex male n(%)6643(81)11(85)ns
Tobacco (pack-year)6642 ± 1138 ± 11ns
Anthropometry
 Weight (kg)6672 ± 1969 ± 16ns
 BMI (kg/m2)6626.5 ± 6.524.7 ± 6.5ns
 BMI < 20 n(%) 7(13)5(38)p < 0.001
 FFMI (kg/m2)5217.2 ± 2.515.7 ± 1.7p = 0.05
 Low FFMI < 18♂ & < 15♀ n(%) 24(57)9(90)p < 0.001
History of exacerbations
 Exacerbations (n)661.21 ± 1.21.85 ± 0.9p < 0.05
 Frequent exacerbators (%) 19(36)8(62)p < 0.001
Blood test and flow cytometry
 Eosinophils (total/mm3)66206 ± 176173 ± 104ns
 Eosinophils > 300/mm3 (%) 15(28)2(15)p < 0.05
 HCMV+ (%)3528(88)3(100)ns
 NK5918.7 ± 1020.5 ± 8ns
 NKG2A+4630.1 ± 1822.2 ± 9ns
Functional testing
 FEV1 (% pred.) pre/post bd6637 ± 13/39 ± 1437 ± 18/38 ± 21ns
 FEV1/FVC (%) pre/post bd6644 ± 11/44 ± 1145 ± 13/46 ± 14ns
 RV/TLC (%)6063 ± 1063 ± 16ns
 DLco (% pred.)6045 ± 1843 ± 29ns
 Kco (% pred.)6052 ± 2049 ± 24ns
 SpO2 (%)6693 ± 392 ± 4ns
 6MWT (m)56362 ± 118350 ± 141ns
CT Scan
 Emphysema (%)5837(80)7(58)p < 0.01
 Bronchiectasis (%)5810(22)3(25)ns
  1. Data are represented as means ± standard deviation or n(percentages). Abbreviations: BMI body mass index; FFMI fat free mass index; HCMV human cytomegalovirus; NK Natural Killer cells; FEV1 forced expiratory volume in the first second; bd bronchodilator; FVC forced vital capacity; RV residual volume; TLC total lung capacity; DLco carbon monoxide transfer coefficient; Kco Krogh index (DLco/alveolar volume; SpO2 oxygen saturation (pulse oximetry); 6MWT six-minute walking test distance; CT computed tomography,