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Fig. 6 | Respiratory Research

Fig. 6

From: HDAC8 inhibitor attenuates airway responses to antigen stimulus through synchronously suppressing galectin-3 expression and reducing macrophage-2 polarization

Fig. 6

Double immunofluorescent staining of HDAC8 and Cal-3 expression. Expressions of HDAC8 (bright orange) and Cal-3 (green) in lung specimens (a) and macrophages (b) were identified according to the image results. An increase in the HDAC8 expression level was synchronously associated with the same change of Cal-3 expression in the OVA-treated lungs and IL-4-treated cells. Treatment with BUD and PCI resulted in visualising parallel reduction of the expression levels of both proteins in the investigated samples

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