Effect of average volume-assured pressure support treatment on health-related quality of life in COPD patients with chronic hypercapnic respiratory failure: a randomized trial

Table 2 Gase exchange

Variables	Patients treated with AVAPS		Control group		Treatment Effect (95% CI) 6 months–baseline	P- Value
Variables	Baseline	After 6 month	Baseline	After 6 month	Treatment Effect (95% CI) 6 months–baseline	P- Value
Pa CO₂ mm Hg	54.8 ± 3.5	46.6 ± 3.1	54.5 ± 3.3	48.3 ± 3.9	0.6 (−0.3 to 0.9)	0.001*
PaO₂ mm Hg	50.7 ± 2.1	59.6 ± 2.3	50.9 ± 2.5	57.7 ± 3.2	0.6(−0.67 to 0.56	0.001*
HCO₃⁻, mmol/L	34.2 ± 3.1	29.5 ± 2.1	34.9 ± 3.2	30.6 ± 2.9	0.4(−1.4 to 1.6)	0.001*

Data are shown as mean ± SD. A positive mean difference means an increase from baseline to 6 months for AVAPS compared with control group. HCO₃⁻ = bicarbonate; PaCO2, partial arterial carbon dioxide pressure; PaO2, partial arterial oxygen pressure

ISSN: 1465-993X