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Table 1 Differentially expressed genes

From: Cigarette smoke and electronic cigarettes differentially activate bronchial epithelial cells

Exclusively upregulated genesSymbol
Upregulated exclusively by ECIG compared to Ctr > 1.30 (range depicted 1.37–1.31, descending order)CYP2A6, ZNF286A, APOBEC3B, WDR57, LPCAT2, LYPD2, CYP2B7P1, SLCO2A1
Upregulated exclusively by TCIG compared to ECIG > 1.30 (range depicted 1.52–1.33, descending order)ARHGEF16, GDF15, PRDM1, RINT1, NTHL1, CYB5R2, CYP4F12, TNFRSF10A, RGS19, EDC3, APN5, SLC35C1, OTUB2, B3GNT8, ULK3, KRT18P17, CDC37L1, MAFF, CYP4F22, EHBP1L1
Upregulated exclusively by TCIG compared to Ctr > 1.30 (range depicted 1.56–1.45, descending order)MAOB, IGSF5, CEP55, SPRED2, CICE, FKBP4, NIT2, MTHFS, NAPG, GDPD3, FEZ1, IFRD2, FOSL1, SHISA2, MVD, WDR72, AMN1, CYBASC3, GATC, IL1F5
Exclusively downregulated genes
 Downregulated exclusively by ECIG compared to Ctr < 0.60 (range depicted 0.56–0.59, increasing order)C14orf85, NBPF8, CYP3A5, SNORA61, FLJ36131
 Downregulated exclusively by TCIG compared to ECIG < 0.60 (range depicted 0.45–0.58, increasing order)CYP2A6, SLCO2A1, HSPB3, TPM1, LYPD2, CA9, ALOX5AP, RTDR1, APCDD1, CYP4X1, C13orf30, SCARA3, MGC39900, RSPH9, MYLK, NGB, PPM1E, DNAI1, PTPRZ1, TSPAN8
 Downregulated exclusively by TCIG compared to Ctr < 0.60 (range depicted 0.49–0.58 increasing order)RYR3, DNAH12L, ODZ3, S100A3, AHNAK2, MIR221, ENC1, SMA4, TNFAIP8L1, MIR21, FLJ44342, TTC18, MEX3B, RGMA, FLJ23834, MAFB, MMP13, DNHD2, C1orf63, DCBLD1
Commonly deregulated genes
 Upregulated commonly in TCIG/ECIG and TCIG/Ctr > 1.30 (range depicted 37.5–2.50, descending order)CYP1A1, ANXA10, S100A12,PANX2, SLC7A11, CLDN10, UGT1A6, AKR1B15, C9orf169, GPX2, UCHL1, HSD17B2, IL1B, TRIB3, SLC7A5, ZBED2, CYP1B1, ENPEP, S100A7, PRSS3
 Upregulated commonly in ECIG/Ctr and TCIG/Ctr > 1.30 (range depicted 1.37–1.31, descending order)(LOC100128899, LOC391019)
 Downregulated commonly in TCIG/ECIG and TCIG/Ctr < 0.60 (range depicted 0.29–0.42, increasing order)C6orf205, MUC21, TNC, CYP4B1, PPARGC1A, EDN1, TAGLN, LOX, CYP2F1, CALML3, ERP27, MMP10, CDH2, MXRA5, EGFL6, COL4A1, ATP12A, CDH11, UBD, CILP
 Downregulated commonly in TCIG/Ctr and ECIG/Ctr < 0.60 (range depicted 0.51–0.59, increasing order)FAM175A, MIR205, CATSPER2, GABRE, MGC16121
  1. Only the top-20 genes are shown (where possible). For a complete listing see supplemental data