Table 1 Pathways enriched in PPHN-Associated gene variants identified in the tibetan population
From: Frequent mutation of hypoxia-related genes in persistent pulmonary hypertension of the newborn
Pathway name | Pathway ID | PPHN genes (114) | All genes (17251) | P value | Q value |
|---|---|---|---|---|---|
Renal cell carcinoma | ko05211 | 7 | 101 | 4.71E-06 | 0.001 |
Salmonella infection | ko05132 | 10 | 317 | 4.79E-05 | 0.005 |
Pathways in cancer | ko05200 | 14 | 644 | 8.85E-05 | 0.006 |
Graft-versus-host disease | ko05332 | 5 | 74 | 0.0001293 | 0.006 |
HIF-1 signaling pathway | ko04066 | 7 | 185 | 0.0002281 | 0.009 |
Bladder cancer | ko05219 | 4 | 61 | 0.0007062 | 0.023 |
Regulation of actin cytoskeleton | ko04810 | 11 | 588 | 0.0017709 | 0.050 |
Gap junction | ko04540 | 5 | 135 | 0.0020232 | 0.050 |