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Table 2 Pulmonary function parameters before and after Bronchial Thermoplasty treatment

From: Resistance of the respiratory system measured with forced oscillation technique (FOT) correlates with bronchial thermoplasty response

 

Parameter

Before BT

After BT

P-value

Before bronchodilation

FEV1 (% predicted)

88 ± 21

90 ± 21

0.33

FEF 75 (L/s)

1.04 ± 0.57

0.97 ± 0.70

0.44

FVC (% predicted)

98 ± 20

102 ± 17

< 0.05

FEV1/FVC

0.74 ± 0.11

0.73 ± 0.12

0.46

Raw IN (kPa*s/L)

0.30 (0.20;0.42)

0.29 (0.19;0.42)

0.99

FRC (L)

2.60 (1.97;3.22)

2.63 (2.03;3.08)

0.69

RV (L)

1.81 ± 0.74

1.80 ± 0.64

0.68

After bronchodilation

FEV1 (% predicted)

100 ± 18

100 ± 15

0.72

FEF 75 (L/s)

1.28 ± 0.67

1.20 ± 0.78

0.37

FVC (% predicted)

107 ± 15

108 ± 13

0.33

FEV1/FVC

0.79 ± 0.10

0.77 ± 0.10

< 0.05

FEV1 reversibility

11 (3.5;14)

4 (2;15)

0.11

Raw IN (kPa*s/L)

0.15 (0.14;0.21)

0.23 (0.16;0.24)

< 0.05

FRC (L)

2.73 (1.90;3.10)

2.52 (2.00;2.91)

0.14

RV (L)

1.60 ± 0.55

1.65 ± 0.47

0.49

  1. Data are presented as mean (± SD) or median (IQR); n = 23 for pre-bronchodilator measurements and n = 24 for post-bronchodilator measurements
  2. FEV1 forced expiratory volume in 1 second, FEF 75 forced expiratory flow at 75% of the FVC, FVC forced vital capacity, Raw airway resistance, FRC functional residual capacity, RV residual volume