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Table 1 Selection criteria

From: Epigenetics dysfunction in morbid obesity with or without obstructive sleep apnoea: the EPIMOOSA study

INCLUSION CRITERIAEXCLUSION CRITERIA
• Age 18–60 years
• BMI consistently > 40 kg/m2 for 3–5 years, following more than 1 year of unsuccessful controlled medical treatment
• BMI 35–40 kg/m2 with comorbidities susceptible to improvement with weight loss (hypertension, diabetes mellitus, dyslipidemia, OSA, etc.), following more than 1 year of unsuccessful controlled medical treatment
• Signed informed consent form
• Obesity hypoventilation syndrome or treatment with positive pressure devices
• Diagnosis of systemic inflammatory disease
• Neoplastic diseases in the last 5 years
• Previous cardiovascular event (myocardial infarction, stroke or arterial aneurism) in the last 6 months
• Pregnancy